{
  "abstract": "Ulcerative colitis (UC) is a chronic immune-mediated inflammatory bowel disease with an expanding therapeutic landscape and increasing clinical complexity. This guideline was developed by the Korean Association for the Study of Intestinal Diseases (KASID) to provide updated, evidence-based recommendations for the medical management of adult patients with UC in Korea. Guideline development used the GRADE-ADOLOPMENT approach, with source guidelines appraised using AGREE II. Key questions were formulated using the PICO framework, source guidelines and consensus documents published from 2017 through 2025 were appraised, and targeted literature searches covering January 2020 through April 2026 were conducted in PubMed, Embase, the Cochrane Library, and KoreaMed. The guideline addresses induction and maintenance therapy for mild-to-moderate and moderate-to-severe UC, management of acute severe UC, indications for surgery, use of biosimilars and subcutaneous formulations, and treatment optimization and sequencing. Recommendations were formulated based on structured evidence review and Evidence-to-Decision considerations, and were finalized through a modified Delphi consensus process and external review. The final recommendations emphasize objective disease control, individualized treatment selection, timely escalation or surgery in acute severe UC, and shared decision-making based on efficacy, safety, comorbidities, prior treatment exposure, patient preference, drug accessibility, and the Korean healthcare context. This guideline is intended to support consistent, practical, and patient-centered care and to improve long-term outcomes for adults with UC.",
  "abstract_shown": true,
  "affiliations": [
    "전남대학교 의과대학 내과학교실",
    "부산대학교 의과대학 내과학교실",
    "부산대학교병원 소화기내과",
    "부산대학교병원 의생명연구원",
    "중앙대학교 의과대학 내과학교실",
    "대구가톨릭대학교 의과대학 내과학교실",
    "이화여자대학교 의과대학 내과학교실",
    "성균관대학교 의과대학 삼성서울병원 내과학교실",
    "한림대학교 의과대학 춘천성심병원 내과학교실",
    "한림대학교 의과대학 강동성심병원 내과학교실",
    "가톨릭대학교 의과대학 대전성모병원 내과학교실",
    "경북대학교 의과대학 내과학교실",
    "조선대학교 의과대학 내과학교실",
    "가톨릭대학교 의과대학 인천성모병원 내과학교실",
    "연세대학교 의과대학 내과학교실 및 소화기병연구소",
    "울산대학교 의과대학 서울아산병원 소화기내과",
    "연세대학교 원주의과대학 원주의학도서관",
    "한국보건의료연구원",
    "울산대학교 의과대학 서울아산병원 외과 대장항문외과"
  ],
  "article_type": "review article",
  "arxiv": null,
  "author_total": 23,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "동현 김"
    },
    {
      "affs": [
        1
      ],
      "name": "승민 홍"
    },
    {
      "affs": [
        2
      ],
      "name": "승용 신"
    },
    {
      "affs": [
        3
      ],
      "name": "준화 배"
    },
    {
      "affs": [
        4
      ],
      "name": "은미 송"
    },
    {
      "affs": [
        5
      ],
      "name": "지은 김"
    },
    {
      "affs": [
        6
      ],
      "name": "영주 양"
    },
    {
      "affs": [
        7
      ],
      "name": "지영 윤"
    },
    {
      "affs": [
        8
      ],
      "name": "상범 강"
    },
    {
      "affs": [
        9
      ],
      "name": "은수 김"
    },
    {
      "affs": [
        4
      ],
      "name": "성은 김"
    },
    {
      "affs": [
        10
      ],
      "name": "성중 김"
    },
    {
      "affs": [
        10
      ],
      "name": "준 이"
    },
    {
      "affs": [
        11
      ],
      "name": "수영 나"
    },
    {
      "affs": [
        12
      ],
      "name": "수정 박"
    },
    {
      "affs": [
        13
      ],
      "name": "상형 박"
    },
    {
      "affs": [
        14
      ],
      "name": "명하 김"
    },
    {
      "affs": [
        15
      ],
      "name": "미영 최"
    },
    {
      "affs": [
        16
      ],
      "name": "종률 이"
    },
    {
      "affs": [
        17
      ],
      "name": "세진 백"
    },
    {
      "affs": [
        18
      ],
      "name": "원 문",
      "orcid": "0000-0002-3963-8680"
    },
    {
      "affs": [
        4
      ],
      "name": "성애 정",
      "orcid": "0000-0002-3963-8680"
    },
    {
      "name": "대한장연구학회 가이드라인위원회"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/1xat06n08sa8q.bib",
  "cited_by": 0,
  "doi": "10.4166/kjg.2026.091",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13714434/",
  "id": "1xat06n08sa8q",
  "issns": [
    "1598-9992",
    "2233-6869"
  ],
  "landing_url": "https://doi.org/10.4166/kjg.2026.091",
  "language": "ko",
  "licence": "CC-BY-NC-4.0",
  "licence_label": "CC BY-NC 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Lower GI Tract"
    ],
    [
      "heading",
      "REVIEW ARTICLE"
    ],
    [
      "openalex",
      "1311|Inflammatory Bowel Disease"
    ]
  ],
  "openalex": "W7223553189",
  "pdf_url": null,
  "pmcid": "PMC13714434",
  "pmid": "42928006",
  "published": "2026-10-25",
  "publisher": "Korean Society of Gastroenterology",
  "ris": "https://research.draconitic.com/paper/1xat06n08sa8q.ris",
  "sources": [
    {
      "first_seen": "2026-11-01T12:21:56Z",
      "native_id": "PMC13714434",
      "source": "pmc",
      "url": "https://doi.org/10.4166/kjg.2026.091"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:1311|Inflammatory Bowel Disease",
      "subfield": "genetics-genomics"
    }
  ],
  "title": "2026 대한장연구학회 궤양성 대장염 내과적 치료 가이드라인",
  "title_text": "2026 대한장연구학회 궤양성 대장염 내과적 치료 가이드라인",
  "type": "peer-reviewed",
  "updated_at": "2026-11-01T12:21:56Z",
  "url": "https://research.draconitic.com/paper/1xat06n08sa8q",
  "venue": "The Korean Journal of Gastroenterology",
  "versions": []
}