{
  "abstract": "A 31-year-old woman who had been receiving propylthiouracil (PTU) treatment for Graves' disease was referred to our hospital for the evaluation of hematuria and proteinuria. Laboratory tests showed positivity for myeloperoxidase-antineutrophil cytoplasmic antibody (ANCA), proteinase 3-ANCA, and anti-double-stranded DNA antibodies. A kidney biopsy revealed immunocomplex-mediated mesangial proliferative glomerulonephritis, consistent with lupus nephritis (LN) diagnosis. Additionally, tubulitis, peritubular capillaritis without immune complex deposition, and medullary angiitis were observed. We herein describe a case of overlap syndrome of LN and ANCA-associated vasculitis (AAV) that developed during PTU therapy. A detailed histological evaluation, including an examination of the renal medulla, may aid in distinguishing between AAV, LN, and overlap syndromes.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 10,
  "authors": [
    {
      "name": "Shun Yoshida"
    },
    {
      "name": "Daichi Nakagomi"
    },
    {
      "name": "Motohiro Ueda"
    },
    {
      "name": "Kengo Asahina"
    },
    {
      "name": "Keiichi Osano"
    },
    {
      "name": "Toshihisa Ishii"
    },
    {
      "name": "Makiko Konishi"
    },
    {
      "name": "Kazuya Takahashi"
    },
    {
      "name": "Akira Shimizu"
    },
    {
      "name": "Ayumu Nakashima"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/1ycxm91bzezd5.bib",
  "cited_by": 1,
  "doi": "10.2169/internalmedicine.7792-26",
  "fulltext_url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7792-26/_article",
  "id": "1ycxm91bzezd5",
  "issns": [
    "1349-7235",
    "0918-2918"
  ],
  "landing_url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7792-26/_article",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "jstage-journal",
      "medicine/general"
    ],
    [
      "openalex",
      "2740|Vasculitis and related conditions"
    ]
  ],
  "openalex": "W7214573567",
  "pdf_url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7792-26/_pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-29",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/1ycxm91bzezd5.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:31Z",
      "native_id": "10.2169/internalmedicine.7792-26",
      "source": "jstage",
      "url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7792-26/_article"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2740|Vasculitis and related conditions",
      "subfield": "general"
    }
  ],
  "title": "Biopsy-proven Systemic Lupus Erythematosus and Antineutrophil Cytoplasmic Antibody-associated Vasculitis Overlap Syndrome Developed during Propylthiouracil Therapy: A Case-based Review",
  "title_text": "Biopsy-proven Systemic Lupus Erythematosus and Antineutrophil Cytoplasmic Antibody-associated Vasculitis Overlap Syndrome Developed during Propylthiouracil Therapy: A Case-based Review",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:31Z",
  "url": "https://research.draconitic.com/paper/1ycxm91bzezd5",
  "venue": "Internal Medicine",
  "versions": []
}