{
  "abstract": null,
  "abstract_shown": false,
  "affiliations": [
    "Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA",
    "Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA",
    "Aging & Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA",
    "Departments of Biochemistry & Biophysics, and Bioengineering, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA",
    "Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA",
    "Aging and Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA",
    "Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA",
    "Division of Cardiology, Cardiovascular Institute, Children’s Hospital of Philadelphia, Philadelphia, PA, USA",
    "Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 27,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Nicholas Forelli",
      "orcid": "0000-0002-8289-0929"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Trace Thome",
      "orcid": "0000-0003-4823-8547"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Deborah Eaton",
      "orcid": "0000-0002-6913-7668"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Kollin C. Schultz",
      "orcid": "0000-0002-4456-8349"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Jiten D. Patel",
      "orcid": "0009-0007-3072-9205"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Caitlyn E. Bowman",
      "orcid": "0000-0003-2310-581X"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Ryo Kawakami",
      "orcid": "0000-0002-4979-410X"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Jae Woo Jung",
      "orcid": "0000-0001-7178-7400"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Ivan A. Kuznetsov",
      "orcid": "0000-0003-0023-3405"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Kristina Li",
      "orcid": "0000-0002-4417-0998"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Jialiu A. Liang",
      "orcid": "0000-0003-1475-2353"
    },
    {
      "affs": [
        0,
        2
      ],
      "name": "Kirsten Branch"
    },
    {
      "affs": [
        0,
        2
      ],
      "name": "Claire Brady",
      "orcid": "0009-0006-4898-4610"
    },
    {
      "affs": [
        0,
        3
      ],
      "name": "Kenneth C Bedi",
      "orcid": "0000-0003-3588-9324"
    },
    {
      "affs": [
        0,
        3
      ],
      "name": "Yijun Yang",
      "orcid": "0000-0002-6971-2503"
    },
    {
      "affs": [
        0,
        2
      ],
      "name": "Kaustubh Koya",
      "orcid": "0009-0007-8181-2607"
    },
    {
      "affs": [
        0,
        4
      ],
      "name": "Nesrine Bouhrira",
      "orcid": "0000-0002-6406-2302"
    },
    {
      "affs": [
        5,
        1
      ],
      "name": "Emily Megill",
      "orcid": "0000-0002-0244-8779"
    },
    {
      "affs": [
        5,
        1
      ],
      "name": "Daniel S. Kantner",
      "orcid": "0000-0001-7202-1554"
    },
    {
      "affs": [
        6
      ],
      "name": "Louis G. Smith",
      "orcid": "0000-0001-9576-0421"
    },
    {
      "affs": [
        6
      ],
      "name": "Cristin F. MacIntosh",
      "orcid": "0009-0000-8091-0028"
    },
    {
      "affs": [
        6
      ],
      "name": "Kushol Gupta",
      "orcid": "0000-0002-7006-2667"
    },
    {
      "affs": [
        6
      ],
      "name": "Gregory R. Bowman",
      "orcid": "0000-0002-2083-4892"
    },
    {
      "affs": [
        5
      ],
      "name": "Nathaniel W. Snyder",
      "orcid": "0000-0001-5643-8747"
    },
    {
      "affs": [
        7
      ],
      "name": "Jonathan Edwards",
      "orcid": "0000-0002-8153-7066"
    },
    {
      "affs": [
        0
      ],
      "name": "Kenneth B. Margulies",
      "orcid": "0000-0002-8093-4465"
    },
    {
      "affs": [
        0,
        8
      ],
      "name": "Zoltan Pierre Arany",
      "orcid": "0000-0003-1368-2453"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/1yq9r44acx9td.bib",
  "cited_by": 22,
  "doi": "10.1126/science.aeh4856",
  "fulltext_url": null,
  "id": "1yq9r44acx9td",
  "issns": [
    "0036-8075",
    "0193-4511",
    "1095-9203"
  ],
  "landing_url": "https://doi.org/10.1101/2024.07.26.605401",
  "language": "en",
  "licence": "unknown",
  "licence_label": "Licence not stated",
  "licence_source": "unknown",
  "licence_url": null,
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2712|Diabetes Treatment and Management"
    ]
  ],
  "openalex": "W4401047215",
  "pdf_url": null,
  "pmcid": "PMC11291109",
  "pmid": "39091820",
  "published": "2026-08-27",
  "publisher": "American Association for the Advancement of Science",
  "ris": "https://research.draconitic.com/paper/1yq9r44acx9td.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:26:54Z",
      "native_id": "W4401047215",
      "source": "openalex",
      "url": "https://doi.org/10.1101/2024.07.26.605401"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2712|Diabetes Treatment and Management",
      "subfield": "endocrinology-metabolism"
    }
  ],
  "title": "SGLT2 inhibitors activate pantothenate kinase in the human heart",
  "title_text": "SGLT2 inhibitors activate pantothenate kinase in the human heart",
  "type": "peer-reviewed",
  "updated_at": "2026-11-09T13:21:15Z",
  "url": "https://research.draconitic.com/paper/1yq9r44acx9td",
  "venue": "Science",
  "versions": []
}