{
  "abstract": "Objective: To assess the long-term clinical and echocardiographic outcomes of mitral valve surgery with annular decalcification and pericardial patch reconstruction in patients with severe mitral annular calcification (MAC).\n\nPatients and methods: Between 2012 and 2022, 112 consecutive high-risk patients (67 women, 45 men; mean age 66.5 ± 13.6 years) underwent surgery for severe MAC with mitral stenosis and/or regurgitation. Mitral valve repair was performed in 55 patients (49%) and replacement in 57 (51%). Concomitant procedures were performed in 65 patients (58%). Mean follow-up was 97 ± 48 months.\n\nResults: Early mortality was 6.3% ( n = 7) and late mortality was 23.2% ( n = 26). Survival was 89.3%, 77.2%, and 64.1% at 60, 96, and 144 months, respectively. Freedom from reoperation was 98.3% at 60 months and 93.3% at 96 months. At follow-up, no surviving patient had more than grade III mitral regurgitation. Grade III regurgitation was present in 3 patients (4%), while no patient had grade IV regurgitation. Left atrial diameter, left ventricular end-diastolic diameter, and mean transvalvular gradient were significantly lower than before surgery.\n\nConclusion: In this high-risk cohort, annular decalcification and pericardial patch reconstruction provided durable valve function and acceptable long-term survival in patients who survived the perioperative period. Perioperative mortality, however, remained substantial.",
  "abstract_shown": true,
  "affiliations": [
    "Medical Faculty, RWTH Aachen University",
    "Department of Endovascular Surgery, University Clinic of Brandenburg/Havel",
    "Department of Cardiothoracic Surgery, Helios Hospital Siegburg"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Yoganiranjana Dharuman"
    },
    {
      "affs": [
        1
      ],
      "name": "Egan Kalmykov"
    },
    {
      "affs": [
        2
      ],
      "name": "Mirko Doss"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/1zyvytbw6w51z.bib",
  "cited_by": 0,
  "doi": "10.3389/fcvm.2026.1881651",
  "fulltext_url": "https://www.frontiersin.org/articles/10.3389/fcvm.2026.1881651/full",
  "id": "1zyvytbw6w51z",
  "issns": [
    "2297-055X"
  ],
  "landing_url": "https://www.frontiersin.org/articles/10.3389/fcvm.2026.1881651/full",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "RC666-701"
    ],
    [
      "openalex",
      "2705|Cardiac Valve Diseases and Treatments"
    ]
  ],
  "openalex": "W7224094141",
  "pdf_url": "https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2026.1881651/pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-28",
  "publisher": "Frontiers Media SA",
  "ris": "https://research.draconitic.com/paper/1zyvytbw6w51z.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:20:10Z",
      "native_id": "10.3389/fcvm.2026.1881651",
      "source": "crossref",
      "url": "https://www.frontiersin.org/articles/10.3389/fcvm.2026.1881651/full"
    },
    {
      "first_seen": "2026-10-31T14:22:05Z",
      "native_id": "003263aaffe44ccbabcd3e1f050ef1db",
      "source": "doaj",
      "url": "https://doi.org/10.3389/fcvm.2026.1881651"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2705|Cardiac Valve Diseases and Treatments",
      "subfield": "cardiovascular"
    }
  ],
  "title": "Long-term clinical and echocardiographic outcomes after mitral valve surgery for severe mitral annular calcification",
  "title_text": "Long-term clinical and echocardiographic outcomes after mitral valve surgery for severe mitral annular calcification",
  "type": "peer-reviewed",
  "updated_at": "2026-10-31T14:22:05Z",
  "url": "https://research.draconitic.com/paper/1zyvytbw6w51z",
  "venue": "Frontiers in Cardiovascular Medicine",
  "versions": []
}