{
  "abstract": "The origin of genome size variation remains a central question in evolutionary biology. Previous analyses suggest that the energetic costs of small insertions and deletions (indels) influence genome size by altering the cellular energy budget. Here, we present a theoretical framework for genome evolution in phytoplankton-the main producers of the sunlit ocean-whose growth depends on nutrient availability. We derive an expression for the selection coefficient on indels as a function of four parameters, including the minimum amount of nutrient inside the cell. Parameter estimates indicate that 1-bp indels can be counterselected in phytoplankton with minimal nutrient requirements. We then test three predictions of nutrient-driven selection on genome evolution. Altogether, this model provides a quantitative and mathematical basis for the genome streamlining hypothesis.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "name": "Carlos Caceres"
    },
    {
      "name": "Marc Krasovec"
    },
    {
      "name": "Olivier Crispi"
    },
    {
      "name": "Sebastien Gourbiere"
    },
    {
      "name": "Gwenael Piganeau"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/2101dwmy44f3g.bib",
  "cited_by": 0,
  "doi": "10.1126/sciadv.aee2207",
  "fulltext_url": null,
  "id": "2101dwmy44f3g",
  "issns": [
    "2375-2548"
  ],
  "landing_url": "https://hal.science/hal-05348523v2",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
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      "openalex",
      "1311|Evolution and Genetic Dynamics"
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  "openalex": "W4414295152",
  "pdf_url": "https://hal.science/hal-05348523/document",
  "pmcid": null,
  "pmid": "42418574",
  "published": "2026-07-08",
  "publisher": "American Association for the Advancement of Science (AAAS)",
  "ris": "https://research.draconitic.com/paper/2101dwmy44f3g.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:29Z",
      "native_id": "hal-05348523",
      "source": "hal",
      "url": "https://hal.science/hal-05348523v2"
    }
  ],
  "subjects": [
    {
      "field": "biochemistry",
      "origin": "hal:2.sdv.bbm.gtp",
      "subfield": "proteomics-metabolomics"
    },
    {
      "field": "biology",
      "origin": "hal:1.sdv.bibs",
      "subfield": "bioinformatics"
    },
    {
      "field": "biology",
      "origin": "hal:1.sdv.bid",
      "subfield": "ecology"
    },
    {
      "field": "biology",
      "origin": "hal:2.sdv.bid.evo",
      "subfield": "evolutionary-biology"
    },
    {
      "field": "biology",
      "origin": "hal:1.sdv.mp",
      "subfield": "microbiology"
    }
  ],
  "title": "Effect of cellular nutrient economy on the evolution of genome size in phytoplankton",
  "title_text": "Effect of cellular nutrient economy on the evolution of genome size in phytoplankton",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:29Z",
  "url": "https://research.draconitic.com/paper/2101dwmy44f3g",
  "venue": "Science Advances",
  "versions": []
}