{
  "abstract": "Background: Sleep disruptions are common in cancer survivors and can negatively impact quality of life. Young breast cancer survivors face unique challenges and may have distinct sleep patterns. We examined trajectories of insomnia symptoms over 3 years among young survivors.\n\nMethods: 836 women, ≤45 years old with stage I-III breast cancer, were recruited to the Menstrual Cycle Maintenance and Quality of Life After Breast Cancer Study within 8 months of diagnosis. Insomnia symptoms were assessed at 6-month intervals from baseline through 3 years post-recruitment, using the Women’s Health Initiative Insomnia Rating Scale (WHIIRS). Group-based trajectory modeling was used to identify distinct trajectories of insomnia symptoms. The final model was chosen by comparing the average posterior probability of assignment (PPA) and examining the distinctiveness and interpretability of the trajectories. Key demographic, quality of life and clinical variables were assessed in multinomial logistic regression models as potential factors associated with group membership.\n\nResults: The mean age of participants was 38 years (range: 20–45 years) at enrollment. Three distinct insomnia trajectories were identified: low probability of insomnia (n=277, 33.1%), moderate probability (n=354, 42.4%), and high probability (n=205, 24.5%). Average PPA was between 75%-82% for each group. Insomnia symptoms were highest at baseline but improved for the low probability and moderate probability groups. In adjusted models, older age (p=0.02), lower education (p=0.03), having received chemotherapy (p=0.03), night sweats (p=0.02), lower SF-12 physical component scores (poorer physical functioning, p<0.0001), and lower SF-12 mental health component scores (p<0.0001) were associated with participants in the moderate and high probability insomnia groups compared to those in the low probability group.\n\nConclusion: Insomnia symptoms are problematic for many young breast cancer survivors. Future studies are needed to determine whether early identification and intervention can modify these insomnia symptom trajectories and improve broader survivorship outcomes.",
  "abstract_shown": true,
  "affiliations": [
    "Division of Cancer Prevention & Control, College of Medicine, The Ohio State University",
    "The Ohio State University Comprehensive Cancer Center",
    "Center for Biostatistics, Department of Biomedical Informatics, The Ohio State University",
    "Breast Service, Department of Surgery, Memorial Sloan Kettering Cancer Center",
    "Health Texas Community Health Services Corporate Director of Breast Services"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Chloe M. Hery"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Kayla Williams"
    },
    {
      "affs": [
        2
      ],
      "name": "Sarah A. Janse"
    },
    {
      "affs": [
        2
      ],
      "name": "Juan Peng"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Faiza Kalam"
    },
    {
      "affs": [
        3
      ],
      "name": "Kimberly Van Zee"
    },
    {
      "affs": [
        4
      ],
      "name": "Elizabeth Z. Naftalis"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Electra D. Paskett"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Michelle J. Naughton"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/21f1x8dhnayg0.bib",
  "cited_by": 0,
  "doi": "10.3389/fonc.2026.1967396",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13724340/?tool=EBI",
  "id": "21f1x8dhnayg0",
  "issns": [
    "2234-943X"
  ],
  "landing_url": "https://www.frontiersin.org/articles/10.3389/fonc.2026.1967396/full",
  "language": "eng",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Original Research"
    ],
    [
      "openalex",
      "3205|Sleep and related disorders"
    ]
  ],
  "openalex": "W7222930951",
  "pdf_url": "https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2026.1967396/pdf",
  "pmcid": "PMC13724340",
  "pmid": "42973551",
  "published": "2026-10-19",
  "publisher": "Frontiers Media SA",
  "ris": "https://research.draconitic.com/paper/21f1x8dhnayg0.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:20:13Z",
      "native_id": "10.3389/fonc.2026.1967396",
      "source": "crossref",
      "url": "https://www.frontiersin.org/articles/10.3389/fonc.2026.1967396/full"
    },
    {
      "first_seen": "2026-11-03T15:20:51Z",
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      "source": "europepmc",
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  "subjects": [
    {
      "field": "medicine",
      "origin": "issn:2234-943X",
      "subfield": "oncology"
    }
  ],
  "title": "Three-year trajectories of insomnia symptoms among young breast cancer survivors",
  "title_text": "Three-year trajectories of insomnia symptoms among young breast cancer survivors",
  "type": "peer-reviewed",
  "updated_at": "2026-11-05T12:21:06Z",
  "url": "https://research.draconitic.com/paper/21f1x8dhnayg0",
  "venue": "Frontiers in Oncology",
  "versions": []
}