{
  "abstract": "The Duroc-derived reference genome Sscrofa11.1 has provided a critical foundation for pig genomics, supporting accurate variant detection and comparative analyses, but does not capture breed-specific variation. Here, we present a near-complete genome assembly for the Landrace pig (Landrace_v1, GCA_963921485.1), spanning all 20 chromosomes and totaling 2.6 Gb, including 176 Mb of sequence absent from Sscrofa11.1. Comparative analyses with recently published high-quality pig genomes reveals conserved centromere organization across breeds, accompanied by substantial variation in repeat composition and length, and identifies a pig-specific pattern of telomere variant repeats across eight breeds. The improved resolution of repetitive regions in Landrace_v1 enables more complete reconstruction of complex gene families, including olfactory receptors, and uncovers structural variation at the KIT proto-oncogene receptor tyrosine kinase locus absent from the Duroc reference. Together, these findings highlight limitations of single-reference genomes and demonstrate the value of breed-specific assemblies for capturing genomic diversity and improving downstream analyses.",
  "abstract_shown": true,
  "affiliations": [
    "Centre for Integrative Genetics (CIGENE), Department of Animal and Aquacultural Sciences, Faculty of Biosciences, Norwegian University of Life Sciences (NMBU) , Ås 1433 ,",
    "Geno SA , Hamar 2317 ,",
    "Norsvin SA , Hamar 2317 ,"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Harald Grove"
    },
    {
      "affs": [
        0
      ],
      "name": "Kristina Stenløkk"
    },
    {
      "affs": [
        0
      ],
      "name": "Sigbjørn Lien"
    },
    {
      "affs": [
        1
      ],
      "name": "Arne Gjuvsland"
    },
    {
      "affs": [
        0
      ],
      "name": "Mariann Árnyasi"
    },
    {
      "affs": [
        2
      ],
      "name": "Maren van Son",
      "orcid": "0000-0002-4892-3387"
    },
    {
      "affs": [
        0
      ],
      "name": "Matthew Kent"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/21nexbf19hevm.bib",
  "cited_by": 0,
  "doi": "10.1093/g3journal/jkag289",
  "fulltext_url": null,
  "id": "21nexbf19hevm",
  "issns": [
    "2160-1836"
  ],
  "landing_url": "https://academic.oup.com/g3journal/advance-article/doi/10.1093/g3journal/jkag289/9002842",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1311|Genetic and phenotypic traits in livestock"
    ]
  ],
  "openalex": "W7223957872",
  "pdf_url": "https://academic.oup.com/g3journal/advance-article-pdf/doi/10.1093/g3journal/jkag289/72534563/jkag289.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-27",
  "publisher": "Oxford University Press (OUP)",
  "ris": "https://research.draconitic.com/paper/21nexbf19hevm.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:09Z",
      "native_id": "10.1093/g3journal/jkag289",
      "source": "crossref",
      "url": "https://academic.oup.com/g3journal/advance-article/doi/10.1093/g3journal/jkag289/9002842"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:1311|Genetic and phenotypic traits in livestock",
      "subfield": "genetics-genomics"
    }
  ],
  "title": "A near-complete Landrace pig ( Sus scrofa ) genome resolves centromeres and telomeres and highlights telomere repeat structures in different pig breeds",
  "title_text": "A near-complete Landrace pig ( Sus scrofa ) genome resolves centromeres and telomeres and highlights telomere repeat structures in different pig breeds",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:09Z",
  "url": "https://research.draconitic.com/paper/21nexbf19hevm",
  "venue": "G3: Genes, Genomes, Genetics",
  "versions": []
}