{
  "abstract": "Background: Primary Percutaneous Coronary Intervention (pPCI) is the preferred reperfusion strategy in ST-elevation myocardial infarction (STEMI). However, concerns remain regarding potential delays and adverse outcomes during off-hours (nights, weekends, and holidays). This study compared clinical outcomes between on-hours and off-hours pPCI, focusing on Door-to-Balloon (D2B) time and Major Adverse Cardiovascular Events (MACE).\n\nMethods: We conducted a single-center retrospective cohort study of consecutive patients with ST-Elevation Myocardial Infarction (STEMI) who underwent pPCI at Harapan Kita National Cardiovascular Center, Jakarta, Indonesia, between January 2023 and April 2024. On-hours were weekdays 08:00–20:00; all other times were off-hours. Only hemodynamically stable STEMI patients were included. The primary outcome was D2B (D2B) time, and the secondary outcome was 1-year MACE, defined as a composite of urgent revascularization, recurrent myocardial infarction, cardiovascular death, or stroke/Transient Ischemic Attack (TIA). Continuous variables were compared using the Mann–Whitney U test, and categorical variables using the chi-square test. Logistic regression analysis was performed to assess the association between off-hours PCI and clinical outcomes.\n\nResults: Among 287 patients, 98 presented during on-hours and 189 during off-hours. Baseline age was similar (median 55–56 years). Median D2B time was shorter on off-hours: 80 [Interquartile Range (IQR) 70–104] vs 89 [74–121] minutes (p=0.018). The proportion achieving D2B <90 minutes did not differ (63.5% vs 58.2%; p=0.443). At 1 year, MACE rates were comparable (14.8% off-hours vs 17.3% on-hours, p=0.576), with no significant differences across individual components.\n\nConclusions: In this real-world cohort from a tertiary cardiac hospital in Indonesia, off-hours presentation was associated with faster D2B times and no increase in 1-year MACE, suggesting consistent quality and efficiency of STEMI care across all hours.",
  "abstract_shown": true,
  "affiliations": [
    "Faculty of Medicine, Universitas Andalas, Padang, Indonesia",
    "Invasive Diagnostic and Non-Surgical Intervention Division, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia",
    "Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia",
    "Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Reforma Setiana"
    },
    {
      "affs": [
        1
      ],
      "name": "Doni Firman"
    },
    {
      "affs": [
        2
      ],
      "name": "Callista Rizvidella"
    },
    {
      "affs": [
        3
      ],
      "name": "Daniel Valentino Chrismara"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/21ryx0sj4qvq5.bib",
  "cited_by": 0,
  "doi": "10.30701/ijc.2043",
  "fulltext_url": "https://www.ijconline.id/index.php/ijc/article/view/2043",
  "id": "21ryx0sj4qvq5",
  "issns": [
    "0126-3773",
    "2620-4762"
  ],
  "landing_url": "https://doi.org/10.30701/ijc.2043",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "RC666-701"
    ],
    [
      "openalex",
      "2705|Acute Myocardial Infarction Research"
    ]
  ],
  "openalex": "W7223575134",
  "pdf_url": "https://www.ijconline.id/index.php/ijc/article/download/2043/828",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-25",
  "publisher": "Indonesian Heart Association",
  "ris": "https://research.draconitic.com/paper/21ryx0sj4qvq5.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:46:47Z",
      "native_id": "025cfd3d963e449da1f036bd4db75312",
      "source": "doaj",
      "url": "https://doi.org/10.30701/ijc.2043"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2705|Acute Myocardial Infarction Research",
      "subfield": "cardiovascular"
    }
  ],
  "title": "On-Hours Versus Off-Hours Primary PCI for STEMI: Outcomes in a Real-World Tertiary Hospital Cohort",
  "title_text": "On-Hours Versus Off-Hours Primary PCI for STEMI: Outcomes in a Real-World Tertiary Hospital Cohort",
  "type": "peer-reviewed",
  "updated_at": "2026-10-31T14:20:54Z",
  "url": "https://research.draconitic.com/paper/21ryx0sj4qvq5",
  "venue": "Majalah Kardiologi Indonesia",
  "versions": []
}