{
  "abstract": "Objective: We aimed to investigate the efficacy of transcervical esophageal sonoelastography in discriminating between patients with and without Reflux Esophagitis (RE).\n\nMethods: Patients who underwent an esophagogastroduodenoscopy following a transcervical sonoelastographic examination in a tertiary center were included. The thickness and Shear Wave Velocity (SWV) of the submucosa-mucosa, muscularis mucosae, and total esophageal wall were measured by using sonoelastography. Patients were classified into RE-positive (grades A-D according to The Los Angeles Classification) and RE-negative groups based on endoscopic findings. The elastosonographic features of RE (-) and RE (+) patients were compared statistically\n\nResults: Among the 503 included patients, 129 (25.6%) were RE (+) [(80 grade A (62%), 28 grade B (21.7%), 12 grade C (9.3%), 9 grade D (7%)] and 374 were RE (-). A 31.7% positive correlation between age and Total Wall Thickness (TWT) and a 21% negative correlation between TWT and submucosa-mucosa SWV were detected. The thickness of submucosa-mucosa, muscularis propria, and total wall were significantly higher in RE (+) patients compared to RE (-) patients (p < 0.001 for all). The SWVs of submucosa-mucosa, muscularis propria, and total wall were significantly lower in RE (+) patients compared to RE (-) patients (p < 0.001 for all). A cut-off value of 2.35 mm for TWT yielded 67% sensitivity and 57% specificity, while a cut-off of 2.08 m/s for total wall SWV yielded 79% sensitivity and 81% specificity for the diagnosis of RE.\n\nDiscussion: The significant increase in cervical esophageal wall thickness in RE (+) is consistent with the literature. However, the markedly decreased stiffness is a novel finding demonstrated by this study.\n\nConclusion: The evaluation of esophageal thickness and stiffness using sonoelastography may be added to routine neck ultrasound scans for the prediction of RE.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Radiology, University of Health Sciences Van Research and Training Hospital, Van, Türkiye",
    "Department of Radiology, Van Yuzuncu Yıl University School of Medicine, Van, Türkiye",
    "Department of Gastroenterology, Ministry of Health Siirt Training Hospital, Siirt Training Hospital, Siirt, Türkiye",
    "Department of Gastroenterology, Health Sciences University Izmir Tepecik Eğitin ve Araştırma Hastanesi, Izmir, Türkiye",
    "Department of Radiology, Kırşehir Ahi Evran University, Faculty of Medicine, Kırşehir, Türkiye"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 10,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Gökhan Aygün"
    },
    {
      "affs": [
        1
      ],
      "name": "Sercan Özkaçmaz",
      "orcid": "0000-0002-9245-0206"
    },
    {
      "affs": [
        1
      ],
      "name": "Fatma Durmaz",
      "orcid": "0000-0003-3089-7165"
    },
    {
      "affs": [
        1
      ],
      "name": "Mesut Özgökçe",
      "orcid": "0000-0002-3095-2446"
    },
    {
      "affs": [
        1
      ],
      "name": "Ilyas Dündar",
      "orcid": "0000-0002-1429-077X"
    },
    {
      "affs": [
        1
      ],
      "name": "Nurşen Toprak",
      "orcid": "0000-0002-9759-9093"
    },
    {
      "affs": [
        2
      ],
      "name": "Yaren Dirik",
      "orcid": "0000-0003-4582-8672"
    },
    {
      "affs": [
        3
      ],
      "name": "Mesut Aydın",
      "orcid": "0000-0002-7411-1067"
    },
    {
      "affs": [
        4
      ],
      "name": "Yeliz Dadalı",
      "orcid": "0000-0002-9277-5078"
    },
    {
      "affs": [
        1
      ],
      "name": "Harun Elçiçek",
      "orcid": "0009-0003-7588-0110"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/22nvkrm3ehb1f.bib",
  "cited_by": 0,
  "doi": "10.2174/0115734056462689260813104254",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13736226/",
  "id": "22nvkrm3ehb1f",
  "issns": [
    "1573-4056"
  ],
  "landing_url": "https://doi.org/10.2174/0115734056462689260813104254",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Medicine, Imaging, Radiology, Nuclear Medicine"
    ],
    [
      "openalex",
      "2741|Ultrasound Imaging and Elastography"
    ]
  ],
  "openalex": "W7204748323",
  "pdf_url": null,
  "pmcid": "PMC13736226",
  "pmid": "42693861",
  "published": "2026-08-24",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/22nvkrm3ehb1f.ris",
  "sources": [
    {
      "first_seen": "2026-11-09T12:21:43Z",
      "native_id": "PMC13736226",
      "source": "pmc",
      "url": "https://doi.org/10.2174/0115734056462689260813104254"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2741|Ultrasound Imaging and Elastography",
      "subfield": "imaging"
    }
  ],
  "title": "Can Esophageal Stiffness and Thickness Measurement by Transcervical Sonoelastography Predict Reflux Esophagitis?",
  "title_text": "Can Esophageal Stiffness and Thickness Measurement by Transcervical Sonoelastography Predict Reflux Esophagitis?",
  "type": "peer-reviewed",
  "updated_at": "2026-11-09T12:21:43Z",
  "url": "https://research.draconitic.com/paper/22nvkrm3ehb1f",
  "venue": "Current Medical Imaging",
  "versions": []
}