{
  "abstract": "The latest generation of optically pumped magnetometer (OPM)-based magnetoencephalography (OP-MEG) systems are increasingly portable and lightweight, making the system easier to wear while undertaking large, whole-body translational and rotational movements. We recorded OP-MEG from three participants during auditory stimulation, while the participants walked around a magnetically shielded room, moving across an area of at least 1.7 m2 and rotating by at least 180 degrees. All sensor-specific electronics were housed within a wearable backpack, minimising movement restrictions which would otherwise be imposed by sensor cabling. In this experiment, the maximum peak-to-peak range of the observed magnetic field recorded on a single channel was 25.2 nT, considerably beyond the approximately 4 nT range of many previous OP-MEG systems. We show that adaptive multipole modelling (AMM) with the temporal extension can be used to separate the interference and neuromagnetic signals, despite the large degree of movement and proximity of the sensor electronics. We observed significant auditory evoked responses at the sensor level, without the need for source localisation approaches for interference suppression. These findings demonstrate the capability of OP-MEG for conducting naturalistic experiments involving movement and for recordings with paediatric and clinical cohorts who cannot remain still.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Imaging Neuroscience, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom",
    "Spinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland",
    "Translational Neuromodeling Unit, Institute for Biomedical Engineering, University of Zurich & ETH Zurich, Zurich, Switzerland",
    "QuSpin Inc., Louisville, CO, United States",
    "Oxford Centre for Human Brain Activity (OHBA), Department of Psychiatry, University of Oxford, Oxford, United Kingdom",
    "Department of Neuroscience, Physiology and Pharmacology, University College London, London, United Kingdom",
    "UCL Institute of Cognitive Neuroscience, University College London, London, United Kingdom"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 14,
  "authors": [
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Stephanie Mellor",
      "orcid": "0000-0001-8164-645X"
    },
    {
      "affs": [
        0
      ],
      "name": "Tim M. Tierney"
    },
    {
      "affs": [
        3
      ],
      "name": "James Osborne"
    },
    {
      "affs": [
        0
      ],
      "name": "Meaghan E. Spedden"
    },
    {
      "affs": [
        0,
        4
      ],
      "name": "Robert A. Seymour"
    },
    {
      "affs": [
        0
      ],
      "name": "Nicholas A. Alexander"
    },
    {
      "affs": [
        3
      ],
      "name": "Cody Doyle"
    },
    {
      "affs": [
        3
      ],
      "name": "David Bobela"
    },
    {
      "affs": [
        5
      ],
      "name": "George C. O’Neill"
    },
    {
      "affs": [
        6
      ],
      "name": "Katarzyna Rudzka"
    },
    {
      "affs": [
        0
      ],
      "name": "Sahitya Puvvada"
    },
    {
      "affs": [
        0
      ],
      "name": "Maike Schmidt"
    },
    {
      "affs": [
        3
      ],
      "name": "Vishal Shah"
    },
    {
      "affs": [
        0
      ],
      "name": "Gareth R. Barnes"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/23zayvtzzbdr2.bib",
  "cited_by": 0,
  "doi": "10.1162/imag.a.1424",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13732490/",
  "id": "23zayvtzzbdr2",
  "issns": [
    "2837-6056"
  ],
  "landing_url": "https://doi.org/10.1162/imag.a.1424",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Research Article"
    ],
    [
      "openalex",
      "3107|Atomic and Subatomic Physics Research"
    ]
  ],
  "openalex": "W7220864593",
  "pdf_url": null,
  "pmcid": "PMC13732490",
  "pmid": "42984978",
  "published": "2026-11-03",
  "publisher": "MIT Press",
  "ris": "https://research.draconitic.com/paper/23zayvtzzbdr2.ris",
  "sources": [
    {
      "first_seen": "2026-11-08T12:22:28Z",
      "native_id": "PMC13732490",
      "source": "pmc",
      "url": "https://doi.org/10.1162/imag.a.1424"
    }
  ],
  "subjects": [
    {
      "field": "physics",
      "origin": "openalex:3107|Atomic and Subatomic Physics Research",
      "subfield": "amo"
    }
  ],
  "title": "Auditory evoked responses during ambulatory OP-MEG",
  "title_text": "Auditory evoked responses during ambulatory OP-MEG",
  "type": "peer-reviewed",
  "updated_at": "2026-11-08T12:22:28Z",
  "url": "https://research.draconitic.com/paper/23zayvtzzbdr2",
  "venue": "Imaging Neuroscience",
  "versions": []
}