{
  "abstract": "Objective: The aim of this study was to describe active psychotropic medication records and agent-level patterns in children and adolescents with autism spectrum disorder (ASD), estimate psychotropic polypharmacy, and identify characteristics associated with an active psychotropic medication record. Method: This single-centre retrospective cross-sectional study included patients with ASD aged 36–216 months who attended a tertiary child and adolescent psychiatry clinic during 2025. Of 172 records assessed, five patients with cognitive impairment attributable to an identified cause other than ASD were excluded; 167 were analysed. Current medications not documented as discontinued were classified as active. Polypharmacy was defined as at least two active psychotropic medications at the same visit. Results: At least one active psychotropic medication was recorded for 123 patients (73.7%; 95% CI 66.5%–79.7%), and polypharmacy for 94 (56.3%; 95% CI 48.7%–63.6%); among the 123 patients with an active record, the polypharmacy proportion was 76.4%. At least one antipsychotic was recorded for 112 patients (67.1%) and at least two for 30 (18.0%). ADHD (aPR = 2.51; 95% CI 1.77–3.55) and irritability (aPR = 1.55; 95% CI 1.28–1.89) were independently associated with an active medication record. Conclusion: Active psychotropic medication records and record-based polypharmacy were frequent in this tertiary-care sample, reflecting electronic health record documentation rather than confirmed medication intake.",
  "abstract_shown": true,
  "affiliations": [
    "SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ADANA ŞEHİR SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, ÇOCUK PSİKİYATRİSİ ANABİLİM DALI",
    "ÇUKUROVA ÜNİVERSİTESİ"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Dilek Altun Varmış",
      "orcid": "0000-0001-5968-4740"
    },
    {
      "affs": [
        0
      ],
      "name": "Elif Koçak",
      "orcid": "0009-0005-2681-412X"
    },
    {
      "affs": [
        0
      ],
      "name": "Cumali Yüksekkaya",
      "orcid": "0009-0002-9174-3469"
    },
    {
      "affs": [
        1
      ],
      "name": "Hülya Binokay",
      "orcid": "0000-0002-0162-4574"
    },
    {
      "affs": [
        0
      ],
      "name": "Serkan Güneş",
      "orcid": "0000-0002-8247-2145"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/24emxgjz7v9zc.bib",
  "cited_by": 0,
  "doi": "10.18863/pgy.2017427",
  "fulltext_url": "https://dergipark.org.tr/tr/download/article-file/6333327",
  "id": "24emxgjz7v9zc",
  "issns": [
    "1309-0674",
    "1309-0658"
  ],
  "landing_url": "https://doi.org/10.18863/pgy.2017427",
  "language": "en",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "RC435-571"
    ],
    [
      "openalex",
      "2805|Autism Spectrum Disorder Research"
    ]
  ],
  "openalex": "W7221320813",
  "pdf_url": "https://dergipark.org.tr/en/download/article-file/6333327",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-25",
  "publisher": "Psikiyatride Güncel Yaklaşımlar",
  "ris": "https://research.draconitic.com/paper/24emxgjz7v9zc.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:46:48Z",
      "native_id": "6ed216d9cc0e4566b57af6b1ca0e3292",
      "source": "doaj",
      "url": "https://doi.org/10.18863/pgy.2017427"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:2805|Autism Spectrum Disorder Research",
      "subfield": "neuroscience"
    }
  ],
  "title": "Active Psychotropic Medication Use and Clinical Correlates in Children and Adolescents with Autism Spectrum Disorder",
  "title_text": "Active Psychotropic Medication Use and Clinical Correlates in Children and Adolescents with Autism Spectrum Disorder",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:46:48Z",
  "url": "https://research.draconitic.com/paper/24emxgjz7v9zc",
  "venue": "Psikiyatride Güncel Yaklaşımlar",
  "versions": []
}