{
  "abstract": "Introduction. Inferior vena cava filters (IVCF) are an option in patients with acute venous thromboembolism (VTE) with a coexisting absolute contraindication to anticoagulation to reduce the risk of fatal pulmonary embolism. Cancer patients are at high risk of both VTE, bleeding, and death, and the benefits of IVCF insertion in cancer-associated thrombosis (CAT) are uncertain. Objectives: to investigate the indications for optional IVCF, their retrieval rates, and complications in patients with CAT compared to cancer-free patients with VTE. Design: retrospective cohort study in two tertiary care hospitals. Participants. consecutive patients diagnosed with symptomatic VTE and undergoing optional IVCF placement from 2018 and 2022 and a follow-up of two years. Primary outcome measures. IVCF retrieval rates and complications, thromboembolic complications, and short (within 30 days) and long-term (24 months) all-cause mortality. Results. 334 patients (171 women—53%, median age 75.5 years) were included. IVCF was inserted pre-operatively in 156 patients (47%), of whom 107 (68%) had CAT. Non-preoperative IVCF was inserted in 178 patients, of whom 74 (41%) had CAT, 136 (76%) had major bleeding, and 41 (12.3%) were at high bleeding risk. IVFC was removed in 135 patients (40.4%), with a similar rate of filter thrombosis (13.5% vs. 10.4%; p=0.73) and removal (41% vs. 46%; p=0.9) among cancer and cancer-free patients. VTE recurrence or progression was similar between cancer and non-cancer patients (13% vs 12%) over 24 months. Non-preoperative IVCF was associated with a higher mortality rate at 30 days after IVCF insertion in both CAT and cancer-free patients. All-cause mortality between 31 days and 24 months after filter insertion was higher in cancer than non-cancer patients (p=0.0001). Conclusions. Thrombotic complications after IVCF insertion were similar in CAT and non-cancer patients. Short-term mortality was higher after nonoperative than after preoperative filter insertion in both CAT and cancer-free patients. However, patients with CAT had a higher long-term all-cause mortality, regardless of IVCF indication and removal.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 1,
  "authors": [
    {
      "name": "Benilde Cosmi"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/252k8tc1fy6wj.bib",
  "cited_by": 0,
  "doi": null,
  "fulltext_url": "https://www.btvb.org/btvb/article/view/715",
  "id": "252k8tc1fy6wj",
  "issns": [
    "2785-5309"
  ],
  "landing_url": "https://www.btvb.org/btvb/article/view/715",
  "language": "en",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "RC666-701"
    ]
  ],
  "openalex": null,
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-26",
  "publisher": "PAGEPress Publications",
  "ris": "https://research.draconitic.com/paper/252k8tc1fy6wj.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:47:32Z",
      "native_id": "ba1163cdca0448baaf5d1dc36e4febe4",
      "source": "doaj",
      "url": "https://www.btvb.org/btvb/article/view/715"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "lcc:RC666-701",
      "subfield": "cardiovascular"
    }
  ],
  "title": "CO013 | INDICATIONS AND OUTCOMES OF OPTIONAL INFERIOR CAVA FILTERS IN CANCER-ASSOCIATED THROMBOSIS AND IN NON CANCER PATENTS WITH VENOUS THROMBOEMBOLISM",
  "title_text": "CO013 | INDICATIONS AND OUTCOMES OF OPTIONAL INFERIOR CAVA FILTERS IN CANCER-ASSOCIATED THROMBOSIS AND IN NON CANCER PATENTS WITH VENOUS THROMBOEMBOLISM",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:47:32Z",
  "url": "https://research.draconitic.com/paper/252k8tc1fy6wj",
  "venue": "Bleeding, Thrombosis and Vascular Biology",
  "versions": []
}