{
  "abstract": "BACKGROUND: Blood donation candidates who are deferred are not targeted by any health policy.\n\nOBJECTIVES: To describe sociodemographic characteristics of unsuitable blood donation candidates, the causes of unsuitability and compare the prevalence rates of transfusion-transmitted infections in deferred and eligible blood donors.\n\nMETHODS: A cross-sectional survey was conducted to obtain sociodemographic data and blood samples; 8,159 blood donation candidates were screened (21.1% rejected, 78.9% approved). A sample of 212 deferred candidates was established.\n\nFINDINGS: Most rejected candidates were female, young adults, with high school or university education, self-declared white, born in the North region and single. Main reasons for unsuitability were low haemoglobin concentration, potential exposure to malaria and risky sexual behaviour. The comparison of seropositivity rates in deferred and eligible blood donation candidates generated the following prevalence ratios (PR) and respective 95% confidence intervals (CI): human immunodeficiency virus (HIV), PR = 6.75 (1.46 - 31.05), p = 0.046; syphilis, PR = 1.47 (0.46 - 4.64), p = 0.463; anti-HBc, PR = 2.84 (1.24 - 6.50); p = 0.023; anti-HCV, PR = 4.67 (1.06 - 20.58), p = 0,080; Chagas disease, PR = 60.75 (5.53 - 667.43), p = 0.003.\n\nMAIN CONCLUSIONS: Treating anaemia in women and controlling malaria in Roraima will reduce the pool of rejected blood donation candidates in the State.",
  "abstract_shown": true,
  "affiliations": [
    "Fundação Oswaldo Cruz-Fiocruz, Instituto Oswaldo Cruz, Laboratório de Epidemiologia e Sistemática Molecular, Rio de Janeiro, RJ, Brasil",
    "Laboratório Central de Saúde Pública de Roraima, Setor de Imunologia/Parasitologia, Boa Vista, RR, Brasil",
    "Universidade Federal de Roraima, Centro de Estudos da Biodiversidade, Laboratório de Biologia Molecular, Boa Vista, RR, Brasil"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Daniela Ribeiro Roque"
    },
    {
      "affs": [
        2
      ],
      "name": "Fabiana Granja"
    },
    {
      "affs": [
        0
      ],
      "name": "Filipe Anibal Carvalho-Costa",
      "orcid": "0000-0001-8083-2840"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/26hj88mtdcbj9.bib",
  "cited_by": 0,
  "doi": "10.1590/0074-02760250320",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13722438/?tool=EBI",
  "id": "26hj88mtdcbj9",
  "issns": [
    "0074-0276",
    "1678-8060"
  ],
  "landing_url": "https://europepmc.org/article/PMC/PMC13722438",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Research Article"
    ],
    [
      "openalex",
      "1405|Blood donation and transfusion practices"
    ]
  ],
  "openalex": "W4413076626",
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13722438/pdf/?tool=EBI",
  "pmcid": "PMC13722438",
  "pmid": null,
  "published": "2026-10-30",
  "publisher": "Instituto Oswaldo Cruz",
  "ris": "https://research.draconitic.com/paper/26hj88mtdcbj9.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T12:21:37Z",
      "native_id": "PMC:PMC13722438",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13722438"
    },
    {
      "first_seen": "2026-11-03T12:22:56Z",
      "native_id": "PMC13722438",
      "source": "pmc",
      "url": "https://doi.org/10.1590/0074-02760250320"
    }
  ],
  "subjects": [],
  "title": "Blood donation candidates who are deferred in the State of Roraima, Brazilian Amazon: reasons for unsuitability and seroprevalence of transfusion-transmitted pathogens",
  "title_text": "Blood donation candidates who are deferred in the State of Roraima, Brazilian Amazon: reasons for unsuitability and seroprevalence of transfusion-transmitted pathogens",
  "type": "peer-reviewed",
  "updated_at": "2026-11-03T12:22:56Z",
  "url": "https://research.draconitic.com/paper/26hj88mtdcbj9",
  "venue": "Memorias do Instituto Oswaldo Cruz",
  "versions": []
}