{
  "abstract": "Nuclear magnetic resonance (NMR) spectroscopy is a powerful probe of molecular structure and dynamics but typically requires large spin ensembles. Here, we demonstrate nanoscale NMR detection of fluorinated DNA using individual near-surface nitrogen-vacancy (NV) centers in diamond nanopillar waveguides under ambient conditions. We covalently tether $^{19}$F-labeled oligonucleotides to mixed nitrogen- and oxygen-terminated surfaces, localizing target spins within the nanoscale sensing volume. Probabilistic spin simulations suggest that the measured signals are consistent with those expected from a few molecules and depend strongly on NV-molecule separation, configuration, and local surface heterogeneity. These results establish a framework for NMR of surface-tethered biomolecules and identify key challenges for single-molecule structural elucidation.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": "2609.05570",
  "author_total": 5,
  "authors": [
    {
      "name": "Erika Janitz"
    },
    {
      "name": "Konstantin Herb"
    },
    {
      "name": "Laura A. Völker"
    },
    {
      "name": "Christian L. Degen"
    },
    {
      "name": "John M. Abendroth"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/29923cazd9xfq.bib",
  "cited_by": 0,
  "doi": "10.48550/arxiv.2609.05570",
  "fulltext_url": null,
  "id": "29923cazd9xfq",
  "issns": [],
  "landing_url": "https://arxiv.org/abs/2609.05570",
  "language": null,
  "licence": "LicenseRef-arXiv-nonexclusive-1.0",
  "licence_label": "arXiv licence",
  "licence_source": "article",
  "licence_url": "http://arxiv.org/licenses/nonexclusive-distrib/1.0/",
  "metadata_licence": "CC0-1.0",
  "native_subjects": [
    [
      "arxiv",
      "physics.app-ph"
    ],
    [
      "arxiv",
      "physics.ins-det"
    ],
    [
      "arxiv",
      "quant-ph"
    ],
    [
      "openalex",
      "2505|Diamond and Carbon-based Materials Research"
    ]
  ],
  "openalex": "W7211988615",
  "pdf_url": "https://arxiv.org/pdf/2609.05570",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-04",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/29923cazd9xfq.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:48Z",
      "native_id": "2609.05570",
      "source": "arxiv",
      "url": "https://arxiv.org/abs/2609.05570"
    }
  ],
  "subjects": [
    {
      "field": "physics",
      "origin": "arxiv:physics.app-ph",
      "subfield": "applied-instrumentation"
    },
    {
      "field": "physics",
      "origin": "arxiv:quant-ph",
      "subfield": "quantum"
    }
  ],
  "title": "Nanoscale NMR of DNA-Functionalized Diamond Using Individual NV Centers",
  "title_text": "Nanoscale NMR of DNA-Functionalized Diamond Using Individual NV Centers",
  "type": "preprint",
  "updated_at": "2026-10-30T12:19:48Z",
  "url": "https://research.draconitic.com/paper/29923cazd9xfq",
  "venue": "arXiv",
  "versions": []
}