{
  "abstract": "Background/Objectives: Preservation of anterograde ejaculation after transurethral incision for primary bladder neck obstruction (PBNO) has traditionally been assessed with unvalidated binary self-report. We prospectively evaluated ejaculatory and erectile function after the ZANCLE (“Z” Anatomical Needle Cut Leads Ejaculation) technique using two validated patient-reported outcome instruments, the Male Sexual Health Questionnaire–Ejaculatory Dysfunction Short Form (MSHQ-EjD-SF) and the International Index of Erectile Function-5 (IIEF-5). Methods: Forty consecutive patients undergoing ZANCLE for PBNO at a single institution were prospectively enrolled between June 2024 and July 2025. MSHQ-EjD-SF (ejaculatory function domain, items for force/volume/frequency, independent bother item) and IIEF-5 were administered at baseline and at 1, 6, and 12 months postoperatively, together with the binary anterograde-ejaculation question used in the parent cohort. Voiding parameters (Qmax, IPSS, PVR) are not described here, as they have already been reported for this technique by our group in a previously published series. Results: Median age was 41 years (IQR 35–55). The MSHQ-EjD-SF function domain score was unchanged from baseline to 12 months (10.8 ± 1.3 vs. 11.0 ± 1.1, Δ+0.2, p = 0.52), while the bother item improved significantly (1.1 ± 0.9 vs. 0.5 ± 0.6, Δ−0.6, p = 0.011). IIEF-5 total score remained stable throughout follow-up (20.1 ± 3.0 vs. 20.5 ± 2.8 at 12 months, Δ+0.4, p = 0.58). Anterograde ejaculation was preserved by binary self-report in 100% of evaluable patients at every postoperative timepoint. Conclusions: Validated instruments confirm, with greater granularity than binary self-report, that the ZANCLE technique preserves ejaculatory function domain scores and erectile function while reducing ejaculation-related bother. These preliminary findings support incorporation of MSHQ-EjD-SF and IIEF-5 into future prospective evaluations of ejaculation-sparing bladder neck surgery.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Urology, San Carlo di Nancy Hospital, GVM Care and Research, 00165 Rome, Italy"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Alessandro Calarco"
    },
    {
      "affs": [
        0
      ],
      "name": "Pietro Morgia"
    },
    {
      "affs": [
        0
      ],
      "name": "Carlo Maria Scornajenghi"
    },
    {
      "affs": [
        0
      ],
      "name": "Marianna Paolillo"
    },
    {
      "affs": [
        0
      ],
      "name": "Pietro Viscuso"
    },
    {
      "affs": [
        0
      ],
      "name": "Beatrice Filippi"
    },
    {
      "affs": [
        0
      ],
      "name": "Antonio Tufano"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/2ad09exd6hxny.bib",
  "cited_by": 0,
  "doi": "10.3390/jcm15197699",
  "fulltext_url": null,
  "id": "2ad09exd6hxny",
  "issns": [
    "2077-0383"
  ],
  "landing_url": "https://www.mdpi.com/2077-0383/15/19/7699",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2748|Urinary Bladder and Prostate Research"
    ]
  ],
  "openalex": "W7220433872",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-05",
  "publisher": "MDPI AG",
  "ris": "https://research.draconitic.com/paper/2ad09exd6hxny.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:20:00Z",
      "native_id": "10.3390/jcm15197699",
      "source": "crossref",
      "url": "https://www.mdpi.com/2077-0383/15/19/7699"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2748|Urinary Bladder and Prostate Research",
      "subfield": "general"
    }
  ],
  "title": "Validated Assessment of Ejaculatory and Erectile Function After Unilateral “Z”-Shaped Bladder Neck Incision (ZANCLE): A Prospective Study Using the MSHQ-EjD Short Form and IIEF-5",
  "title_text": "Validated Assessment of Ejaculatory and Erectile Function After Unilateral “Z”-Shaped Bladder Neck Incision (ZANCLE): A Prospective Study Using the MSHQ-EjD Short Form and IIEF-5",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:20:00Z",
  "url": "https://research.draconitic.com/paper/2ad09exd6hxny",
  "venue": "Journal of Clinical Medicine",
  "versions": []
}