{
  "abstract": "目的: 颈椎后路手术是治疗颈椎疾病的常见术式，围手术期疼痛控制不足可严重影响患者恢复。竖脊肌平面阻滞(erector spinae plane block，ESPB)已在胸腰椎手术中显示出良好的镇痛效果，但在中老年颈椎后路手术患者的围手术期镇痛效果尚需进一步验证。本研究旨在评估超声引导下ESPB对中老年颈椎后路手术患者围手术期镇痛效果的影响。\n\n方法: 选取64名2024年8月1日至2025年3月31日在中南大学湘雅二医院脊柱外科接受颈椎后路手术的中老年(≥45岁)患者作为研究对象，按1꞉1的比例随机分配到ESPB组和全身麻醉(general anesthesia，GA)组。ESPB组在GA后接受超声引导下ESPB，而GA组仅接受GA。主要结局为术中舒芬太尼用量；次要结局包括术后24 h和48 h的15项恢复质量量表(Quality of Recovery-15，QoR-15)评分，术后不同时间点的数字分级评分法(Numerical Rating Scale，NRS)评分，手术室内多时间点的平均动脉压(mean arterial pressure，MAP)，术后补救镇痛、拔管时间、麻醉复苏时间、术后住院时间及与神经阻滞相关的并发症。比较ESPB组与GA组不同结局指标的差异。\n\n结果: 最终60名参与者完成研究(GA组29名，ESPB组31名)，ESPB组患者术中舒芬太尼用量显著少于GA组[0.42(0.36，0.52) μg/kg vs 0.76(0.64，0.88) μg/kg，P<0.001]。ESPB组患者在术后24 h[121.00(118.00，123.00) vs 118.00(115.00，120.00)，P<0.05]和48 h[124.00(121.00，127.00) vs 123.00(119.00，125.00)，P<0.05]的QoR-15评分均明显高于GA组。在术后24 h和48 h，ESPB组静息或活动时的NRS评分始终低于GA组，两组间差异具有统计学意义(均P<0.001)。与GA组相比，ESPB组的拔管时间明显缩短(P<0.05)、中重度疼痛发生率明显降低(P<0.05)。两组间麻醉复苏时间、术后住院时间及补救镇痛发生率的差异均无统计学意义(均P>0.05)。研究期间未观察到与神经阻滞相关的并发症。\n\n结论: 超声引导下ESPB可显著减少中老年颈椎后路手术患者术中阿片类药物用量，降低术后疼痛评分，缩短拔管时间，并在一定程度上改善术后早期恢复质量。ESPB可能是一种安全有效的围手术期镇痛策略。",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "name": "兴华 江",
      "orcid": "0000-0001-6752-9441"
    },
    {
      "name": "莉洁 徐"
    },
    {
      "name": "宇龙 崔"
    },
    {
      "name": "颜林 郭"
    },
    {
      "name": "军美 徐"
    },
    {
      "name": "丽君 曹",
      "orcid": "0000-0003-4728-9633"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/2aqc8f8kgkc4r.bib",
  "cited_by": 0,
  "doi": "10.11817/j.issn.1672-7347.2026.260191",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13710909/",
  "id": "2aqc8f8kgkc4r",
  "issns": [
    "1672-7347"
  ],
  "landing_url": "https://doi.org/10.11817/j.issn.1672-7347.2026.260191",
  "language": "zh",
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Articles"
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      "openalex",
      "2746|Anesthesia and Pain Management"
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  "openalex": "W7223956336",
  "pdf_url": null,
  "pmcid": "PMC13710909",
  "pmid": "42935201",
  "published": "2026-08-28",
  "publisher": "Central South University",
  "ris": "https://research.draconitic.com/paper/2aqc8f8kgkc4r.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T12:21:46Z",
      "native_id": "PMC13710909",
      "source": "pmc",
      "url": "https://doi.org/10.11817/j.issn.1672-7347.2026.260191"
    }
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  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2746|Anesthesia and Pain Management",
      "subfield": "surgery"
    }
  ],
  "title": "超声引导下竖脊肌平面阻滞对颈椎后路手术中老年患者围手术期镇痛效果的影响：一项前瞻性随机对照研究",
  "title_text": "超声引导下竖脊肌平面阻滞对颈椎后路手术中老年患者围手术期镇痛效果的影响：一项前瞻性随机对照研究",
  "type": "peer-reviewed",
  "updated_at": "2026-10-31T12:21:46Z",
  "url": "https://research.draconitic.com/paper/2aqc8f8kgkc4r",
  "venue": "Journal of Central South University Medical Sciences",
  "versions": []
}