{
  "abstract": "The aim of this narrative review is to present current data on the use of porcine type I collagen (tropocollagen) injections in the treatment of chronic musculoskeletal disorders, with particular emphasis on its clinical application and safety profile. A search was conducted in the Medline/PubMed, Scopus, and Directory of Open Access Journals (DOAJ) databases. Based on inclusion and exclusion criteria, 14 publications were identified. The available studies cover the use of collagen administered intra-articularly, periarticularly, and via mesotherapy. The analyzed publications reported improvements in clinical symptoms and function in various chronic musculoskeletal conditions, accompanied by a favorable safety profile. However, it should be emphasized that the available clinical evidence is limited by small sample sizes, heterogeneity in treatment protocols, and a relatively short follow-up period. Injectable porcine type I collagen is a promising adjunctive treatment for chronic musculoskeletal disorders; however, further, well-designed randomized clinical trials with larger patient cohorts and longer follow-up periods are necessary.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Musculoskeletal Disorders, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland. kamil.aikido@interia.pl."
  ],
  "article_type": "review article",
  "arxiv": null,
  "author_total": 1,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Kamil Koszela",
      "orcid": "0000-0003-3629-7523"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/2bk76t1et5tyn.bib",
  "cited_by": 0,
  "doi": "10.1007/s00296-026-06326-7",
  "fulltext_url": "https://europepmc.org/articles/PMC13652760",
  "id": "2bk76t1et5tyn",
  "issns": [
    "0172-8172",
    "1437-160X"
  ],
  "landing_url": "https://europepmc.org/article/MED/42853282",
  "language": "eng",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2745|Osteoarthritis Treatment and Mechanisms"
    ]
  ],
  "openalex": "W7221125931",
  "pdf_url": "https://europepmc.org/articles/PMC13652760?pdf=render",
  "pmcid": "PMC13652760",
  "pmid": "42853282",
  "published": "2026-10-09",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/2bk76t1et5tyn.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:12Z",
      "native_id": "MED:42853282",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42853282"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2745|Osteoarthritis Treatment and Mechanisms",
      "subfield": "general"
    }
  ],
  "title": "The role of injectable porcine type I collagen (Tropocollagen) in chronic musculoskeletal disorders.",
  "title_text": "The role of injectable porcine type I collagen (Tropocollagen) in chronic musculoskeletal disorders.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:18:12Z",
  "url": "https://research.draconitic.com/paper/2bk76t1et5tyn",
  "venue": "Rheumatology international",
  "versions": []
}