{
  "abstract": "A flexible and promising method for creating polymeric nanofibrous composites for BTE (bone tissue engineering) is electrospinning. The optimal composites should resemble bone's natural ECM (extracellular matrix), possess suitable surface chemistry, exhibit strong mechanical strength, and demonstrate bioactivity and biocompatibility. Selecting the appropriate material for composite fabrication is a critical initial step in developing a BTE (tissue engineered) product. BTE is a multidisciplinary area that applies engineering concepts to bone-related biological processes. Key considerations in this field include composites, cells, growth factors, and their interfaces in the microenvironment. This review article examines the recent developments in BTE using biomimetic electrospun polymeric biomaterials. It provides an overview of Natural polymer, synthetic polymer, bone structure, biocomposite discusses the ideal characteristics of bone scaffolds, and offers a basic introduction to BTE. The fabrication of bone composites is explored in detail, including various materials and techniques used. Additionally covered the characteristics, benefits, and uses of electrospinning in BTE. The application of electrospun nanofibrous composites composed of natural and synthetic polymers for BTE is thoroughly reviewed and discussed, as well as the biomineralization processes involved. Finally, the study concludes with insights into biomimetic composites for BTE based on electrospun nanofibers.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Chemistry, Vellore Institute of Technology, Vellore, Tamil Nadu, 632014, India.",
    "Department of Chemistry, Faculty of Engineering and Technology, SRM Institute Science and Technology, Bharathi Salai, Ramapuram, Chennai, Tamil Nadu, 600089, India.",
    "Nanomaterials Laboratory, Department of Chemistry, Kalasalingam Academy of Research and Education, Krishnankoil, Tamil Nadu, 626126, India.",
    "Department of Chemistry, Faculty of Engineering and Technology, SRM Institute Science and Technology, Bharathi Salai, Ramapuram, Chennai, Tamil Nadu, 600089, India. manikank7@srmist.edu.in.",
    "Department of Chemistry, Karpagam Academy of Higher Education, Coimbatore, Tamil Nadu, 641021, India. manikandan.frsc@gmail.com.",
    "Centre for Advanced Solar Cell Technologies, Karpagam Academy of Higher Education, Coimbatore, Tamil Nadu, 641021, India. manikandan.frsc@gmail.com.",
    "Department of Electrical Engineering, College of Engineering, University of Bisha, P.O. Box 551, 61922, Bisha, Saudi Arabia.",
    "Department of Mechanical Engineering, Adama Science and Technology University, 2552, Adama, Ethiopia. abinet.gosaye@astu.edu.et."
  ],
  "article_type": "review article",
  "arxiv": null,
  "author_total": 8,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "N Valarmathi"
    },
    {
      "affs": [
        0
      ],
      "name": "S Sumathi"
    },
    {
      "affs": [
        1
      ],
      "name": "Helen P Kavitha"
    },
    {
      "affs": [
        2
      ],
      "name": "M Swaminathan"
    },
    {
      "affs": [
        3
      ],
      "name": "Manikandan Krishnamurthy"
    },
    {
      "affs": [
        4,
        5
      ],
      "name": "Manikandan Ayyar"
    },
    {
      "affs": [
        6
      ],
      "name": "Abdullatif Hakami"
    },
    {
      "affs": [
        7
      ],
      "name": "Abinet Gosaye Ayanie",
      "orcid": "0009-0000-0730-0477"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/2e9zpvx9hcj7g.bib",
  "cited_by": 0,
  "doi": "10.1186/s12938-026-01596-5",
  "fulltext_url": "https://europepmc.org/articles/PMC13679161",
  "id": "2e9zpvx9hcj7g",
  "issns": [
    "1475-925X"
  ],
  "landing_url": "https://europepmc.org/article/MED/42897607",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "R855-855.5"
    ],
    [
      "openalex",
      "2204|Bone Tissue Engineering Materials"
    ]
  ],
  "openalex": "W7170191505",
  "pdf_url": "https://europepmc.org/articles/PMC13679161?pdf=render",
  "pmcid": "PMC13679161",
  "pmid": "42897607",
  "published": "2026-07-01",
  "publisher": "BMC",
  "ris": "https://research.draconitic.com/paper/2e9zpvx9hcj7g.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:41Z",
      "native_id": "MED:42897607",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42897607"
    },
    {
      "first_seen": "2026-10-30T13:46:10Z",
      "native_id": "5829dbb8c3e743fdaea63fa860dc9c05",
      "source": "doaj",
      "url": "https://doi.org/10.1186/s12938-026-01596-5"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "lcc:R855-855.5",
      "subfield": "general"
    }
  ],
  "title": "Biomimetic electrospun nanofibrous composites for bone tissue engineering: a review of materials, fabrication, and applications.",
  "title_text": "Biomimetic electrospun nanofibrous composites for bone tissue engineering: a review of materials, fabrication, and applications.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:46:10Z",
  "url": "https://research.draconitic.com/paper/2e9zpvx9hcj7g",
  "venue": "Biomedical engineering online",
  "versions": []
}