{
  "abstract": "Plants deploy direct and indirect defenses in response to insect herbivory. The specific antiherbivore responses involve cell surface immune receptors that recognize herbivore-associated molecular patterns (HAMPs), yet the ecological relevance of this molecular interplay in natural settings remains unexplored. Here, we demonstrate with laboratory and field experimentation in Mexico that the inceptin receptor (INR) in the leaves of common bean orchestrates a tritrophic interaction upon recognition of inceptin, a HAMP in caterpillar oral secretions. Near-isogenic lines with a naturally occurring null mutation in INR revealed that inceptin recognition does not only amplify the wound response but activates an herbivore-specific immune pathway to trigger the emission of a distinctive volatile blend that recruits predatory wasps to effectively remove caterpillars from the plants. These findings provide a definitive molecular-to-ecological link, revealing how a single immune receptor mediates ecologically relevant plant-insect-predator interactions in nature.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Biology, University of Washington, Seattle, WA, USA",
    "Department of Natural Sciences, Converse University, Spartanburg, SC, USA",
    "Laboratory of Evolutionary Entomology, Institute of Biology, University of Neuchâtel, Neuchâtel, 2000 Switzerland",
    "Department of Natural Sciences, Converse University, Spartanburg, 2902 SC, USA",
    "Laboratory of Evolutionary Entomology, Institute of Biology, University of Neuchâtel, Neuchâtel, 000 Switzerland",
    "Department of Plant and Microbial Biology, University of California Berkeley, Berkeley, CA, USA",
    "Department of Plant & Microbial Biology, University of California Berkeley. Berkeley, CA, USA",
    "Section of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA, USA",
    "Department of Entomology, The Pennsylvania State University, University Park, Pennsylvania, USA",
    "State Key Laboratory of Crop Stress Adaptation and Improvement, State Key Laboratory of Cotton Bio-breeding and Integrated Utilization, School of Life Sciences, Henan University, Kaifeng, 475004, China",
    "Department of Entomology, The Pennsylvania State University, University Park, PA, USA",
    "Laboratory of Fundamental and Applied Research in Chemical Ecology, University of Neuchâtel, Neuchâtel 2000, Switzerland",
    "Laboratory of Plant-Insect Research for Sustainable Agriculture (PIRSA), State Key Laboratory of Cotton Bio-breeding and Integrated Utilization, School of Life Sciences, Henan University, Kaifeng 475004, China",
    "Department of Biology, University of Washington. Seattle, WA, USA"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 11,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Natalia Guayazán Palacios",
      "orcid": "0000-0003-3403-6661"
    },
    {
      "affs": [
        1,
        2,
        3,
        4
      ],
      "name": "Patrick Grof‐Tisza",
      "orcid": "0000-0002-0217-4253"
    },
    {
      "affs": [
        0
      ],
      "name": "Brian Behnken",
      "orcid": "0009-0006-4939-556X"
    },
    {
      "affs": [
        2,
        4
      ],
      "name": "Carla Marques Arce"
    },
    {
      "affs": [
        0
      ],
      "name": "Di Wu",
      "orcid": "0000-0003-2202-1921"
    },
    {
      "affs": [
        0,
        5,
        6
      ],
      "name": "Antonio F. Chaparro"
    },
    {
      "affs": [
        0,
        7
      ],
      "name": "Benjamin D. Sheppard",
      "orcid": "0009-0006-3387-0573"
    },
    {
      "affs": [
        7,
        8,
        9
      ],
      "name": "Eric A. Schmelz",
      "orcid": "0000-0002-2837-734X"
    },
    {
      "affs": [
        10,
        11,
        12,
        8,
        9
      ],
      "name": "Ted C. J. Turlings",
      "orcid": "0000-0002-8315-785X"
    },
    {
      "affs": [
        10,
        2,
        12,
        13
      ],
      "name": "Betty Benrey",
      "orcid": "0000-0002-3230-4450"
    },
    {
      "affs": [
        0
      ],
      "name": "Adam D. Steinbrenner",
      "orcid": "0000-0002-7493-678X"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/2emp90y887hbp.bib",
  "cited_by": 5,
  "doi": "10.1126/sciadv.aec3229",
  "fulltext_url": null,
  "id": "2emp90y887hbp",
  "issns": [
    "2375-2548"
  ],
  "landing_url": "https://doi.org/10.1126/sciadv.aec3229",
  "language": "en",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1109|Insect-Plant Interactions and Control"
    ]
  ],
  "openalex": "W4412833447",
  "pdf_url": null,
  "pmcid": "PMC12324489",
  "pmid": "40766452",
  "published": "2026-05-27",
  "publisher": "American Association for the Advancement of Science",
  "ris": "https://research.draconitic.com/paper/2emp90y887hbp.ris",
  "sources": [
    {
      "first_seen": "2026-11-04T13:21:09Z",
      "native_id": "W4412833447",
      "source": "openalex",
      "url": "https://doi.org/10.1126/sciadv.aec3229"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:1109|Insect-Plant Interactions and Control",
      "subfield": "zoology-behaviour"
    }
  ],
  "title": "A plant immune receptor mediates tritrophic interactions by linking caterpillar detection to predator recruitment",
  "title_text": "A plant immune receptor mediates tritrophic interactions by linking caterpillar detection to predator recruitment",
  "type": "peer-reviewed",
  "updated_at": "2026-11-06T13:20:32Z",
  "url": "https://research.draconitic.com/paper/2emp90y887hbp",
  "venue": "Science Advances",
  "versions": []
}