{
  "abstract": "Background: Platelet-rich plasma (PRP) is an autologous concentrate obtained by differential centrifugation of whole blood, yielding platelets 4-7 times the baseline concentration with an attendant payload of growth factors including PDGF, VEGF, EGF, FGF, TGF-β, and IGF-1, which promote cellular proliferation, collagen synthesis, and tissue regeneration. Material and Methods: A prospective interventional study enrolling 50 patients (20 androgenetic alopecia [AGA], 15 acne scars, 15 non-healing venous ulcers) was conducted at a tertiary care centre in western India from December 2020 to September 2022. PRP was prepared by the manual double-spin method and administered intralesionally at 15-day intervals for 3 months (6 sessions), with monthly follow-up until 6 months. Outcomes were assessed by physician’s global assessment (7-point scale), Hamilton-Norwood/Ludwig grading (AGA), Goodman and Baron’s scale (acne scars), and wound area and volume measurements. Results: In AGA, 85% showed improvement (mild 45%, moderate 30%, excellent 10%). In acne scars, 73.3% achieved good-to-excellent objective response; 26-50% improvement was most frequent (53.3%). In non-healing venous ulcers, mean wound area reduced by 68% (14.09 cm² to 6.01 cm²) and volume by 66% (4.74 cm³ to 1.61 cm³), with 46.67% achieving excellent response. No serious adverse events were recorded in any group. Conclusion: PRP is a safe, cost-effective, and efficacious autologous treatment for androgenetic alopecia, acne scars, and non-healing venous ulcers with a favourable side-effect profile.",
  "abstract_shown": true,
  "affiliations": [
    "Assure Clinic, Ahmedabad, Gujarat, India",
    "Department of Dermatology, Venereology & Leprosy, Gujarat Adani Institute of Medical Sciences (GAIMS), GK General Hospital, Bhuj, Kutch, Gujarat, India",
    "Divine Hospital, Jamnagar, Gujarat, India",
    "Vcare Centre of Excellence, Bengaluru, India",
    "Serenity Skin & Aesthetic Clinic, Rajkot, Gujarat, India"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Krunal Dudhatra"
    },
    {
      "affs": [
        1
      ],
      "name": "Jui Shah"
    },
    {
      "affs": [
        2
      ],
      "name": "Mansi Pithadia"
    },
    {
      "affs": [
        1
      ],
      "name": "Devendra Parmar"
    },
    {
      "affs": [
        3
      ],
      "name": "Meera Patel"
    },
    {
      "affs": [
        4
      ],
      "name": "Prerakkumar Kathiriya"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/2g2e6ebr7943y.bib",
  "cited_by": 0,
  "doi": "10.5281/zenodo.23470605",
  "fulltext_url": "https://gjms.gaims.ac.in/index.php/gjms/article/view/555/286",
  "id": "2g2e6ebr7943y",
  "issns": [
    "2583-1763"
  ],
  "landing_url": "https://doi.org/10.5281/zenodo.23470605",
  "language": "en",
  "licence": "CC-BY-NC-SA",
  "licence_label": "CC BY-NC-SA",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-sa/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "R5-920"
    ]
  ],
  "openalex": null,
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-23",
  "publisher": "Gujarat Adani Institute of Medical Sciences",
  "ris": "https://research.draconitic.com/paper/2g2e6ebr7943y.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:44:02Z",
      "native_id": "fa34a93a2c9e436aa8c29b5c2bcf9bd1",
      "source": "doaj",
      "url": "https://doi.org/10.5281/zenodo.23470605"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "lcc:R5-920",
      "subfield": "general"
    }
  ],
  "title": "Efficacy of Platelet-Rich Plasma (PRP) in Androgenetic Alopecia, Acne Scars, and Non-Healing Ulcers: A Prospective Interventional Study",
  "title_text": "Efficacy of Platelet-Rich Plasma (PRP) in Androgenetic Alopecia, Acne Scars, and Non-Healing Ulcers: A Prospective Interventional Study",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:44:02Z",
  "url": "https://research.draconitic.com/paper/2g2e6ebr7943y",
  "venue": "GAIMS Journal of Medical Sciences",
  "versions": []
}