{
  "abstract": "Despite recent advances in climate change attribution, many health impacts remain unmeasured 1 . Here we leverage over a century of clinical data 2 to investigate whether human-caused climate change has increased the burden of childhood malaria across sub-Saharan Africa. We find a robust effect of temperature and extreme precipitation on prevalence, consistent with previous findings at local scales and in laboratory experiments. We estimate that rising temperatures have probably increased malaria in East and southern Africa, but averted a comparable number of cases in West Africa, with a net impact of 1 excess case per 1,000 children (95% confidence interval (CI) −4 to 6) across the continent. Over the coming century, we project that climate change could marginally accelerate the elimination of malaria in West and central Africa, where the present-day burden is highest; across the continent, this could avert 1 (low greenhouse gas emissions: 95% CI −2 to 6) to 20 (high greenhouse gas emissions: 95% CI 0–52) cases per 1,000 children by the end of the century. However, reducing future global warming from 3 °C to under 2 °C could prevent an average of 5 excess cases per 1,000 in high-elevation (more than 1 km) East Africa and in southern Africa (95% CIs −3 to 13 and −4 to 14, respectively) by 2100. Our study resolves a decades-old debate about one of the first suspected health impacts of climate change, providing a template for future work measuring its true global burden.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Epidemiology of Microbial Diseases, Yale University School of Public Health, New Haven, CT, USA. colin.carlson@yale.edu",
    "Public Health Modeling Unit, Yale University School of Public Health, New Haven, CT, USA. colin.carlson@yale.edu",
    "Yale Center on Climate Change and Health, Yale University School of Public Health, New Haven, CT, USA. colin.carlson@yale.edu",
    "Center for Effective Global Action, University of California, Berkeley, Berkeley, CA, USA. tcarleton@berkeley.edu",
    "Department of Agricultural and Resource Economics, University of California, Berkeley, Berkeley, CA, USA. tcarleton@berkeley.edu",
    "National Bureau of Economic Research, Cambridge, MA, USA. tcarleton@berkeley.edu",
    "African Climate and Development Initiative, University of Cape Town, Cape Town, South Africa",
    "Center for Effective Global Action, University of California, Berkeley, Berkeley, CA, USA"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Colin J. Carlson",
      "orcid": "0000-0001-6960-8434"
    },
    {
      "affs": [
        3,
        4,
        5
      ],
      "name": "Tamma A. Carleton",
      "orcid": "0000-0002-5518-0550"
    },
    {
      "affs": [
        6
      ],
      "name": "Romaric C. Odoulami",
      "orcid": "0000-0001-8228-1608"
    },
    {
      "affs": [
        7
      ],
      "name": "Cullen D. Molitor",
      "orcid": "0000-0001-8309-8821"
    },
    {
      "affs": [
        6
      ],
      "name": "Christopher H. Trisos"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/2g6q9qf9pbp3n.bib",
  "cited_by": 24,
  "doi": "10.1038/s41586-026-10840-w",
  "fulltext_url": null,
  "id": "2g6q9qf9pbp3n",
  "issns": [
    "0028-0836",
    "1476-4687"
  ],
  "landing_url": "https://doi.org/10.1038/s41586-026-10840-w",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2307|Climate Change and Health Impacts"
    ]
  ],
  "openalex": "W7171654125",
  "pdf_url": null,
  "pmcid": "PMC13558053",
  "pmid": "42527591",
  "published": "2026-07-29",
  "publisher": "Nature Portfolio",
  "ris": "https://research.draconitic.com/paper/2g6q9qf9pbp3n.ris",
  "sources": [
    {
      "first_seen": "2026-11-04T13:21:16Z",
      "native_id": "W7171654125",
      "source": "openalex",
      "url": "https://doi.org/10.1038/s41586-026-10840-w"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2307|Climate Change and Health Impacts",
      "subfield": "pharmacology-toxicology"
    }
  ],
  "title": "The past and future impact of climate change on childhood malaria in Africa",
  "title_text": "The past and future impact of climate change on childhood malaria in Africa",
  "type": "peer-reviewed",
  "updated_at": "2026-11-09T13:21:20Z",
  "url": "https://research.draconitic.com/paper/2g6q9qf9pbp3n",
  "venue": "Nature",
  "versions": []
}