{
  "abstract": "The Affordable Care Act (ACA) included major coverage expansions implemented in 2014. However, its association with cost‑related barriers among people with chronic disease remains incompletely described. We analyzed trends in cost and transportation related barriers to care between cancer survivors and adults with atherosclerotic cardiovascular disease (ASCVD) in relation to ACA implementation and expansion. National Health Interview Survey (NHIS) data from 2004-2024 for adults ≥18 years reporting a history of cancer or ASCVD without cancer were obtained. Primary outcomes were overall cost‑barrier and transportation barrier. We used survey weighted interrupted time series analysis (ITSA) with prespecified policy breakpoints and survey weighted modified Poisson regression to estimate associations between policy periods and barriers, adjusting for sociodemographic covariates. The analytic sample included 106,947 respondents: 63,505 cancer survivors and 43,442 adults with ASCVD without cancer. Overall cost barriers were reported by 8.1% of cancer survivors (n = 5,264) and 10.6% of adults with ASCVD without cancer (n = 4,772; p < 0.001). In adjusted models, the prevalence of overall cost barriers in 2022–2024 was lower than in 2004–2009 among both cancer survivors (aPR 0.63; 95% CI: 0.56-0.71) and adults with ASCVD without cancer (aPR 0.73; 95% CI: 0.65-0.82). In ITSA, cancer survivors had an immediate decrease in overall cost barriers at the 2022 breakpoint (-1.98 percentage points; p = 0.006). No substantial 2022 level change in overall cost barriers was observed among adults with ASCVD without cancer. Transportation barriers were higher in the post-pandemic period among years with available data, particularly among adults with ASCVD without cancer, but transportation ITSA findings were exploratory since data were unavailable in 2019–2021. Overall cost related barriers declined among U.S. cancer survivors and ASCVD patients, with the largest improvements observed in the most recent period. Nevertheless, increases in transportation-related delays underscore persistent structural barriers and highlight the need for targeted interventions to improve care accessibility.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Surgery, The Ohio State University Wexner Medical Center and James Comprehensive Cancer Center, Columbus, Ohio, United States of America"
  ],
  "article_type": "Research Article",
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Rabia Bega"
    },
    {
      "name": "Qaidar Alizai"
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    {
      "name": "Charalampos M. Charalampous"
    },
    {
      "name": "Areesh Mevawalla"
    },
    {
      "name": "Meher Angez"
    },
    {
      "name": "Rida Ejaz"
    },
    {
      "name": "Lorenza Arena"
    },
    {
      "name": "Jethro Wang Zih-Shuo"
    },
    {
      "name": "Timothy M. Pawlik"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/2hjdwpbm35pnh.bib",
  "cited_by": 0,
  "doi": "10.1371/journal.pgph.0006791",
  "fulltext_url": "https://journals.plos.org/globalpublichealth/article?id=10.1371/journal.pgph.0006791",
  "id": "2hjdwpbm35pnh",
  "issns": [
    "2767-3375"
  ],
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  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2002|Economic and Financial Impacts of Cancer"
    ],
    [
      "plos",
      "/Engineering and technology/Management engineering/Risk management/Insurance"
    ],
    [
      "plos",
      "/Engineering and technology/Transportation"
    ],
    [
      "plos",
      "/Medicine and health sciences/Cardiology/Cardiovascular medicine/Cardiovascular diseases"
    ],
    [
      "plos",
      "/Medicine and health sciences/Health care/Socioeconomic aspects of health"
    ],
    [
      "plos",
      "/Medicine and health sciences/Medical conditions/Cardiovascular diseases"
    ],
    [
      "plos",
      "/Medicine and health sciences/Oncology/Cancers and neoplasms"
    ],
    [
      "plos",
      "/Medicine and health sciences/Public and occupational health/Socioeconomic aspects of health"
    ],
    [
      "plos",
      "/Medicine and health sciences/Vascular medicine/Atherosclerosis"
    ],
    [
      "plos",
      "/Physical sciences/Mathematics/Statistics/Statistical methods/Time series analysis"
    ],
    [
      "plos",
      "/Research and analysis methods/Mathematical and statistical techniques/Statistical methods/Time series analysis"
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      "plos",
      "/Social sciences/Economics/Finance"
    ]
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  "openalex": "W7213532787",
  "pdf_url": "https://journals.plos.org/globalpublichealth/article/file?id=10.1371/journal.pgph.0006791&type=printable",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-18",
  "publisher": "Public Library of Science",
  "ris": "https://research.draconitic.com/paper/2hjdwpbm35pnh.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:49Z",
      "native_id": "10.1371/journal.pgph.0006791",
      "source": "plos",
      "url": "https://journals.plos.org/globalpublichealth/article?id=10.1371/journal.pgph.0006791"
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  "subjects": [
    {
      "field": "mathematics",
      "origin": "plos:statistical methods",
      "subfield": "statistics"
    },
    {
      "field": "medicine",
      "origin": "plos:cardiovascular diseases",
      "subfield": "cardiovascular"
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    {
      "field": "medicine",
      "origin": "plos:cancers and neoplasms",
      "subfield": "oncology"
    }
  ],
  "title": "Cost and transportation barrier trends related to Affordable Care Act among cancer survivors and atherosclerotic cardiovascular disease patients",
  "title_text": "Cost and transportation barrier trends related to Affordable Care Act among cancer survivors and atherosclerotic cardiovascular disease patients",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:49Z",
  "url": "https://research.draconitic.com/paper/2hjdwpbm35pnh",
  "venue": "PLOS Global Public Health",
  "versions": []
}