{
  "abstract": "The osteoclast-like giant cell (OGC) variant of urothelial carcinoma is a rare histological entity characterized by an aggressive clinical course and diagnostic challenges.\n\nWe report the case of a 62-year-old who presented with a muscle-invasive locally advanced urothelial carcinoma of the bladder. the tumor was resistant to chemotherapy. A completely robot-assisted radical cystoprostatectomy (RARC) with an intracorporeal Bricker ileal conduit urinary diversion was successfully performed. Histopathological evaluation of the surgical specimen demonstrated a OGC variant of bladder carcinoma.\n\nThis case highlights the potential chemoresistance of the OGC variant to conventional platinum-based neoadjuvant regimens.",
  "abstract_shown": true,
  "affiliations": [
    "Military Hospital Mohamed V of Rabat, 10100, Morocco"
  ],
  "article_type": "case report",
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Abdelhakim Oukouhou"
    },
    {
      "affs": [
        0
      ],
      "name": "Mohamed Tetou"
    },
    {
      "affs": [
        0
      ],
      "name": "Saad Assila"
    },
    {
      "affs": [
        0
      ],
      "name": "Abdessamad El Bahri"
    },
    {
      "affs": [
        0
      ],
      "name": "Mohamed Alami"
    },
    {
      "affs": [
        0
      ],
      "name": "Ahmed Ameur"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/2jpgpwb6h48n2.bib",
  "cited_by": 0,
  "doi": "10.1016/j.eucr.2026.103643",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13697215/",
  "id": "2jpgpwb6h48n2",
  "issns": [
    "2214-4420"
  ],
  "landing_url": "https://doi.org/10.1016/j.eucr.2026.103643",
  "language": "en",
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Oncology"
    ],
    [
      "openalex",
      "2746|Bladder and Urothelial Cancer Treatments"
    ]
  ],
  "openalex": "W7221549620",
  "pdf_url": "https://europepmc.org/articles/PMC13697215?pdf=render",
  "pmcid": "PMC13697215",
  "pmid": "42935818",
  "published": "2026-10-12",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/2jpgpwb6h48n2.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:18Z",
      "native_id": "PMC13697215",
      "source": "pmc",
      "url": "https://doi.org/10.1016/j.eucr.2026.103643"
    },
    {
      "first_seen": "2026-10-30T12:22:24Z",
      "native_id": "MED:42935818",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42935818"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "heading:Oncology",
      "subfield": "oncology"
    }
  ],
  "title": "Osteoclast-like giant cell variant of bladder urothelial carcinoma with poor response to neoadjuvant chemotherapy managed by robot-assisted radical cystoprostatectomy: A case report",
  "title_text": "Osteoclast-like giant cell variant of bladder urothelial carcinoma with poor response to neoadjuvant chemotherapy managed by robot-assisted radical cystoprostatectomy: A case report",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:34:17Z",
  "url": "https://research.draconitic.com/paper/2jpgpwb6h48n2",
  "venue": "Urology Case Reports",
  "versions": []
}