{
  "abstract": "This study demonstrates the feasibility of fabricating geometry-tunable polydimethylsiloxane (PDMS) intraocular lens (IOL) prototypes using consumer-grade liquid crystal display (LCD) 3D-printed molds and PDMS casting. A reusable mold fabrication strategy incorporating a PMMA barrier layer successfully eliminated PDMS curing inhibition while preserving the mold geometry for repeated casting. The fabrication workflow accurately replicated a plate-haptic lens with a 6 mm optic and dimensional deviation below 1.5%, while enabling optical power to be tuned from 18 to 42 D by varying mold curvature alone. The fabricated PDMS IOLs exhibited high visible-light transparency (>95%), preliminary focusing ability, resolving power and image contrast comparable to a commercial IOL, acceptable post-treatment cytocompatibility, successful injector-assisted delivery with recovery of the original geometry, and preliminary hydrolytic stability and leachability performance. These results establish a reproducible, low-cost, and customizable fabrication platform for PDMS intraocular lenses and provide a foundation for future optimization toward customizable veterinary ophthalmic applications.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": "Article",
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "name": "Suwat Romphosri"
    },
    {
      "name": "Anya Chiradejnant"
    },
    {
      "name": "Titima Lertsrisatit"
    },
    {
      "name": "Orapun Jaturakan"
    },
    {
      "name": "Nalinee Tuntivanich"
    },
    {
      "name": "Sushanta K. Mitra"
    },
    {
      "name": "Charusluk Viphavakit",
      "orcid": "0000-0002-4176-3341"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/2mjqvmyy0nqdw.bib",
  "cited_by": 1,
  "doi": "10.1016/j.isci.2026.117890",
  "fulltext_url": "https://europepmc.org/articles/PMC13694886",
  "id": "2mjqvmyy0nqdw",
  "issns": [
    "2589-0042"
  ],
  "landing_url": "https://www.cell.com/iscience/fulltext/S2589-0042(26)03273-6",
  "language": "eng",
  "licence": "CC-BY-NC-4.0",
  "licence_label": "CC BY-NC 4.0",
  "licence_source": "article",
  "licence_url": "http://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Biomaterials"
    ],
    [
      "heading",
      "Materials science"
    ],
    [
      "heading",
      "Optical Materials"
    ],
    [
      "heading",
      "Veterinary medicine"
    ],
    [
      "openalex",
      "2204|3D Printing in Biomedical Research"
    ]
  ],
  "openalex": "W7221790375",
  "pdf_url": "https://europepmc.org/articles/PMC13694886?pdf=render",
  "pmcid": "PMC13694886",
  "pmid": "42926869",
  "published": "2026-10-14",
  "publisher": "Elsevier BV",
  "ris": "https://research.draconitic.com/paper/2mjqvmyy0nqdw.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:16Z",
      "native_id": "10.1016/j.isci.2026.117890",
      "source": "feed-cell",
      "url": "https://www.cell.com/iscience/fulltext/S2589-0042(26)03273-6"
    },
    {
      "first_seen": "2026-10-30T12:17:49Z",
      "native_id": "10.1016/j.isci.2026.117890",
      "source": "crossref",
      "url": "https://linkinghub.elsevier.com/retrieve/pii/S2589004226032736"
    },
    {
      "first_seen": "2026-10-30T12:21:18Z",
      "native_id": "MED:42926869",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42926869"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "heading:Materials science",
      "subfield": "materials-polymers"
    }
  ],
  "title": "Low-cost geometry-tunable PDMS intraocular lenses fabricated using LCD 3D-printed molds for canine ophthalmic applications",
  "title_text": "Low-cost geometry-tunable PDMS intraocular lenses fabricated using LCD 3D-printed molds for canine ophthalmic applications",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:21:18Z",
  "url": "https://research.draconitic.com/paper/2mjqvmyy0nqdw",
  "venue": "iScience",
  "versions": []
}