{
  "abstract": "The node–module logic underpins DNA, RNA, and metal–organic frameworks. In small-molecule synthesis, SuFEx and PFEx exploit sulfur or phosphorus as single‑atom nodes for 10 modular ligations but are largely confined to amine and phenol modules. Silicon‑based ligation would offer a viable alternative, as both alcohols and phenols can serve as reliable modules, yet it has lacked efficient and controllable platforms. Herein, we report a silicon-noded ligation platform using bis(2,4,6-trimethoxyphenyl)silanes (bis(TMP)silanes) as the ligation hubs, enabling rapid, high-yielding ligation of both alcohol and phenol modules with broad functional-group tolerance.",
  "abstract_shown": true,
  "affiliations": [
    "School of Chemistry, Xi’an Key Laboratory of Sustainable Energy Materials Chemistry",
    "Xi’an Jiaotong University (XJTU"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Jie Wang"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Zhiyou Hu"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Youliang Wang",
      "orcid": "0000-0002-2613-3616"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/2nerptqwfqkj7.bib",
  "cited_by": 0,
  "doi": "10.26434/chemrxiv.15009106/v1",
  "fulltext_url": null,
  "id": "2nerptqwfqkj7",
  "issns": [],
  "landing_url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15009106/v1",
  "language": null,
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1605|Organoboron and organosilicon chemistry"
    ]
  ],
  "openalex": "W7213950314",
  "pdf_url": "https://chemrxiv.org/doi/pdf/10.26434/chemrxiv.15009106/v1",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-20",
  "publisher": "American Chemical Society (ACS)",
  "ris": "https://research.draconitic.com/paper/2nerptqwfqkj7.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:19Z",
      "native_id": "10.26434/chemrxiv.15009106",
      "source": "chemrxiv",
      "url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15009106/v1"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1605|Organoboron and organosilicon chemistry",
      "subfield": "organic"
    }
  ],
  "title": "Rapid, High-Yielding, and Broad-Scope Silicon-Noded Single-Atom Ligation Platform",
  "title_text": "Rapid, High-Yielding, and Broad-Scope Silicon-Noded Single-Atom Ligation Platform",
  "type": "preprint",
  "updated_at": "2026-10-30T12:17:19Z",
  "url": "https://research.draconitic.com/paper/2nerptqwfqkj7",
  "venue": "ChemRxiv",
  "versions": []
}