{
  "abstract": "This study reports the synthesis and characterization of a series of three bis-thiosemicarbazone ligands and their zinc dinuclear complexes, with a focus on 4-tert-butyl-2,6-bis(N-4-allylthiosemicarbazonyl)phenol (H₃L³). This ligand exhibits remarkable photophysical properties and a high analytical performance, acting as a \"turn-on\" fluorescent sensor for Zn²⁺ with a significant fluorescence intensity increase via the chelation-enhanced fluorescence (CHEF) mechanism. The [Zn₂(L³)(OAc)] complex also functions as a \"turn-off\" sensor for pyrophosphate (PPi) anions through a ligand displacement mechanism, showing a good selectivity over other anions, with a low detection limit of 3.5 × 10⁻⁸ M. The probe combines high sensitivity, signal amplification, and selectivity, making a notably effective sensor among those reported. Importantly, H₃L³ demonstrates a good cell-penetrating ability, enabling in vitro imaging of Zn²⁺ without significant cytotoxicity under the studied conditions. These findings highlight its potential as a highly effective fluorescent probe for trace-level detection of Zn²⁺ and advanced analytical applications in complex biological and chemical environments.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 12,
  "authors": [
    {
      "name": "Diana Cebotari"
    },
    {
      "name": "florian vinchon"
    },
    {
      "name": "Salomé Poyer"
    },
    {
      "name": "Maylis Orio"
    },
    {
      "name": "Matthieu Fonvielle"
    },
    {
      "name": "Magali Aumont-Nicaise"
    },
    {
      "name": "Emilie Mérour"
    },
    {
      "name": "Jérôme Bignon"
    },
    {
      "name": "Arnaud Chevalier"
    },
    {
      "name": "Jean-Pierre Mahy"
    },
    {
      "name": "Sebastien Floquet"
    },
    {
      "name": "Rémy Ricoux"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/2pgdcd83n2xpz.bib",
  "cited_by": 0,
  "doi": "10.1016/j.jphotochem.2026.117716",
  "fulltext_url": null,
  "id": "2pgdcd83n2xpz",
  "issns": [
    "1010-6030"
  ],
  "landing_url": "https://hal.science/hal-05799360v1",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.chim"
    ],
    [
      "hal",
      "1.chim.coor"
    ],
    [
      "hal",
      "1.chim.theo"
    ],
    [
      "openalex",
      "1607|Molecular Sensors and Ion Detection"
    ]
  ],
  "openalex": "W7214538233",
  "pdf_url": "https://hal.science/hal-05799360/document",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-14",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/2pgdcd83n2xpz.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:57Z",
      "native_id": "hal-05799360",
      "source": "hal",
      "url": "https://hal.science/hal-05799360v1"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "hal:1.chim.coor",
      "subfield": "inorganic"
    },
    {
      "field": "chemistry",
      "origin": "hal:1.chim.theo",
      "subfield": "theoretical"
    }
  ],
  "title": "Highly sensitive and selective fluorescent bis-thiosemicarbazone chemosensor for dual recognition of Zn²⁺ and pyrophosphate anions (P₂O₇⁴⁻) with bioimaging applications",
  "title_text": "Highly sensitive and selective fluorescent bis-thiosemicarbazone chemosensor for dual recognition of Zn²⁺ and pyrophosphate anions (P₂O₇⁴⁻) with bioimaging applications",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:57Z",
  "url": "https://research.draconitic.com/paper/2pgdcd83n2xpz",
  "venue": "Journal of Photochemistry and Photobiology A: Chemistry",
  "versions": []
}