{
  "abstract": "Visual prostheses have targeted early structures in the visual pathway, including the retina, optic nerve, lateral geniculate nucleus, and visual cortex, to generate visual percepts. Stimulation of higher-order visual regions, which may better encode complex visual features, remains relatively unexplored. We tested whether electrical stimulation of the medial and inferior pulvinar elicits visual percepts in a patient with medically refractory epilepsy undergoing invasive seizure monitoring with intracranial electroencephalography. Bipolar stimulation (30 biphasic pulses, 0.5 ms per phase, 3 mA, 1 Hz) was delivered between adjacent pulvinar contacts while eye movements were tracked. Stimulation of different electrode pairs elicited visual percepts at distinct retinotopic locations (p = 0.010). Stimulation also altered cortical activity, producing an early power increase followed by gamma desynchronization in occipital and parietal regions (p < 0.001) and beta desynchronization in the lateral temporal region (p < 0.01). These findings suggest that pulvinar stimulation can generate visual percepts and modulate distributed cortical networks, supporting further investigation of the pulvinar as a target for vision restoration.",
  "abstract_shown": true,
  "affiliations": [
    "Albert Einstein College of Medicine"
  ],
  "article_type": "New results",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "name": "W. S. Kemball-Cook"
    },
    {
      "name": "E. R. Bader"
    },
    {
      "name": "A. D. Boro"
    },
    {
      "name": "E. N. Eskandar"
    },
    {
      "affs": [
        0
      ],
      "name": "N. J. Killian"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/2syztms1ewr7j.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.09.28.754866",
  "fulltext_url": "https://www.biorxiv.org/content/10.64898/2026.09.28.754866v1.full",
  "id": "2syztms1ewr7j",
  "issns": [],
  "landing_url": "https://www.biorxiv.org/content/10.64898/2026.09.28.754866v1",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "biorxiv",
      "neuroscience"
    ]
  ],
  "openalex": null,
  "pdf_url": "https://www.biorxiv.org/content/10.64898/2026.09.28.754866v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-28",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/2syztms1ewr7j.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:26:19Z",
      "native_id": "10.64898/2026.09.28.754866",
      "source": "biorxiv",
      "url": "https://www.biorxiv.org/content/10.64898/2026.09.28.754866v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "biorxiv:neuroscience",
      "subfield": "neuroscience"
    }
  ],
  "title": "Electrical stimulation of the human pulvinar generates visual percepts",
  "title_text": "Electrical stimulation of the human pulvinar generates visual percepts",
  "type": "preprint",
  "updated_at": "2026-10-30T12:26:19Z",
  "url": "https://research.draconitic.com/paper/2syztms1ewr7j",
  "venue": "bioRxiv",
  "versions": [
    {
      "doi": "10.1016/j.brs.2026.103231",
      "pid": null,
      "relation": "published-as",
      "title": null,
      "venue": null
    }
  ]
}