{
  "abstract": "Cyhalofop-butyl, an aryloxyphenoxypropionate acetyl-CoA carboxylase (ACCase) inhibitor, and quinclorac, a quinolinecarboxylic acid herbicide with auxin-like activity, are commonly used in rice production. This study evaluated the genotoxic potential of the herbicides cyhalofop-butyl and quinclorac in the in vivo Drosophila melanogaster smart assay. Trans-heterozygous larvae obtained from crosses between the multiple wing hairs ( mwh ) and flare -3 ( flr ³ ) strains were exposed to four concentrations (1, 2, 5, and 10 ppm) of each herbicide. Both herbicides significantly increased clone frequencies compared with the negative control. Cyhalofop-butyl exhibited a concentration-related increase in total spot frequencies, whereas quinclorac consistently elevated clone frequencies across all tested concentrations without a clear dose-dependent pattern. To the best of our knowledge, this is the first report demonstrating the genotoxic potential of cyhalofop-butyl. These findings emphasize the need for careful use of herbicides in rice production and support further investigation of alternative products with lower or no genotoxic potential.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 1,
  "authors": [
    {
      "name": "Serap Kocaoğlu-Cenkci"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/2txnbk9js1han.bib",
  "cited_by": 0,
  "doi": "10.7717/peerj.21747",
  "fulltext_url": null,
  "id": "2txnbk9js1han",
  "issns": [
    "2167-8359"
  ],
  "landing_url": "https://peerj.com/articles/21747",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1306|Carcinogens and Genotoxicity Assessment"
    ]
  ],
  "openalex": "W7220450293",
  "pdf_url": "https://peerj.com/articles/21747.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-05",
  "publisher": "PeerJ",
  "ris": "https://research.draconitic.com/paper/2txnbk9js1han.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:47Z",
      "native_id": "10.7717/peerj.21747",
      "source": "crossref",
      "url": "https://peerj.com/articles/21747"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:1306|Carcinogens and Genotoxicity Assessment",
      "subfield": "oncology"
    }
  ],
  "title": "Evaluation of the genotoxic potential of two rice herbicides, cyhalofop-butyl and quinclorac, in Drosophila melanogaster",
  "title_text": "Evaluation of the genotoxic potential of two rice herbicides, cyhalofop-butyl and quinclorac, in Drosophila melanogaster",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:47Z",
  "url": "https://research.draconitic.com/paper/2txnbk9js1han",
  "venue": "PeerJ",
  "versions": []
}