{
  "abstract": "Atherosclerosis (AS), driven by complex cellular interactions, remains a leading cause of mortality worldwide. Conventional therapies often lack diseased blood vessels specificity, limiting therapy efficacy while increasing off-target toxicity. Boasting the biological advantages of cell-derived camouflages, these biomimetic nanomedicines outperform traditional drugs in intraplaque accumulation, circulation half-life and anti-AS efficacy. Current cell-derived biomimetic nanomedicines include whole-cell carriers, cell membrane-coated nanoparticles (NPs), and extracellular vesicles (EVs), all exploitable as novel platforms for plaque imaging and treatment. This review introduces the cellular mechanisms of AS pathology, examines recent advances in biomimetic strategies for AS theranostics and discusses the major barriers in clinical translation including biomaterial design, manufacturing consistency, safety evaluation, and large-scale production.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Radiology, Jinling Hospital, The First School of Clinical Medicine, Southern Medical University, Nanjing, Jiangsu 210008, China.",
    "Department of Radiology, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu 210008, China.",
    "Department of Radiology, Jinling Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210008, China."
  ],
  "article_type": "review article",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Xingji Liu"
    },
    {
      "affs": [
        1
      ],
      "name": "Zhiyue Wang"
    },
    {
      "affs": [
        2
      ],
      "name": "Jiaqi Lu"
    },
    {
      "affs": [
        1
      ],
      "name": "Jie Sheng"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Longjiang Zhang"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/2xt6ew6311wnq.bib",
  "cited_by": 0,
  "doi": "10.7150/thno.133733",
  "fulltext_url": "https://europepmc.org/articles/PMC13684933",
  "id": "2xt6ew6311wnq",
  "issns": [
    "1838-7640"
  ],
  "landing_url": "https://europepmc.org/article/MED/42909371",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2502|Nanoparticle-Based Drug Delivery"
    ]
  ],
  "openalex": "W7214653619",
  "pdf_url": "https://europepmc.org/articles/PMC13684933?pdf=render",
  "pmcid": "PMC13684933",
  "pmid": "42909371",
  "published": "2026-09-09",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/2xt6ew6311wnq.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:20:14Z",
      "native_id": "MED:42909371",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42909371"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:2502|Nanoparticle-Based Drug Delivery",
      "subfield": "materials-polymers"
    }
  ],
  "title": "Cell-derived biomimetic nanomedicines: Emerging theranostic platforms for precision management of atherosclerosis.",
  "title_text": "Cell-derived biomimetic nanomedicines: Emerging theranostic platforms for precision management of atherosclerosis.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:20:14Z",
  "url": "https://research.draconitic.com/paper/2xt6ew6311wnq",
  "venue": "Theranostics",
  "versions": []
}