{
  "abstract": "The industrial application of phenolic acids (PAs) is significantly limited by their low solubility and poor bioavailability in lipid-rich systems. Lipophilization via esterification of PAs with lipid matrices offers a promising approach to address these challenges. In this study, an efficient lipase-chemical catalytic method was developed for synthesizing phenolic acid-esterified phosphatidylcholines (PA-EPCs) from PAs and phosphatidylcholine (PC). Three derivatives-caffeic acid-esterified phosphatidylcholines (CA-EPC), ferulic acid-esterified phosphatidylcholines (FA-EPC), and p-hydroxycinnamic acid-esterified phosphatidylcholines (p-HCA-EPC)-were successfully obtained with isolated yields of 67.5 %, 84.5 %, and 85.3 %, respectively. Their structures were confirmed by 1H/13C NMR and ESI-MS analyses. Compared with unmodified PC, PA-EPCs, especially CA-EPC, showed significantly enhanced in vitro antioxidant activity, as demonstrated by assays of lipid peroxide value, DPPH/ABTS radical scavenging capacity, and ferric reducing antioxidant power (FRAP). Due to the incorporation of PC into PAs, PA-EPCs exhibited enhanced lipophilicity, which significantly improved the stability of oil-in-water (O/W) emulsions. This improvement was evidenced by higher emulsifying activity indices, smaller droplet sizes, more homogeneous distribution, and a slower increase in thiobarbituric acid reactive substances (TBARs) over time. Collectively, these findings indicate that PA-EPCs possess remarkable potential as effective antioxidants and emulsifiers in food, cosmetic, and pharmaceutical industries.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 8,
  "authors": [
    {
      "name": "Hong Li"
    },
    {
      "name": "Xintian Qiao"
    },
    {
      "name": "Ran Ding"
    },
    {
      "name": "Zihao Guo"
    },
    {
      "name": "Desong Zhu"
    },
    {
      "name": "Lu Zhang"
    },
    {
      "name": "Ruiling Shen"
    },
    {
      "name": "Tao Wei"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/2zqzfwsq4nj8n.bib",
  "cited_by": 0,
  "doi": "10.5650/jos.ess25285",
  "fulltext_url": "https://www.jstage.jst.go.jp/article/jos/75/9/75_jos.ess25285/_article",
  "id": "2zqzfwsq4nj8n",
  "issns": [
    "1347-3352",
    "1345-8957"
  ],
  "landing_url": "https://www.jstage.jst.go.jp/article/jos/75/9/75_jos.ess25285/_article",
  "language": null,
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "jstage-journal",
      "chemistry/general"
    ],
    [
      "openalex",
      "1106|Proteins in Food Systems"
    ]
  ],
  "openalex": "W7204842636",
  "pdf_url": "https://www.jstage.jst.go.jp/article/jos/75/9/75_jos.ess25285/_pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-01",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/2zqzfwsq4nj8n.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:38Z",
      "native_id": "10.5650/jos.ess25285",
      "source": "jstage",
      "url": "https://www.jstage.jst.go.jp/article/jos/75/9/75_jos.ess25285/_article"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "jstage-journal:chemistry/general",
      "subfield": "general"
    }
  ],
  "title": "Chemo-enzymatic synthesis, in vitro antioxidant activities and positive effects on oil-in-water emulsion Stabilization of phenolic acid-esterified phosphatidylcholines",
  "title_text": "Chemo-enzymatic synthesis, in vitro antioxidant activities and positive effects on oil-in-water emulsion Stabilization of phenolic acid-esterified phosphatidylcholines",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:38Z",
  "url": "https://research.draconitic.com/paper/2zqzfwsq4nj8n",
  "venue": "Journal of Oleo Science",
  "versions": []
}