{
  "abstract": "STRUCTURED ABSTRACTO_ST_ABSINTRODUCTIONC_ST_ABSThis study examined the extent to which educational attainment, Alzheimers disease (AD) knowledge, and research attitudes are associated with willingness to participate in AD research, and whether AD knowledge and research attitudes mediate associations between educational attainment and willingness to participate.\n\nMETHODS201 older adults completed self-report measures of AD knowledge, research attitudes, prior research participation, and willingness to participate in diagnostic procedures (neuropsychological assessment, blood draw, brain MRI) and non-pharmacological intervention research (tracking physical activity, aerobic exercise).\n\nRESULTSFavorable research attitudes were consistently associated with greater willingness to participate across all proposed research activities, and research attitudes mediated the relationship between educational attainment and willingness to participate in research. In contrast, AD knowledge did not mediate the association between educational attainment and willingness to participate.\n\nDISCUSSIONResearch attitudes may be a key, modifiable determinant of willingness to participate in AD research and a promising focus for broadening AD research participation.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Psychology, The Ohio State University"
  ],
  "article_type": "PUBLISHAHEADOFPRINT",
  "arxiv": null,
  "author_total": 30,
  "authors": [
    {
      "name": "K. M. Bonta"
    },
    {
      "name": "E. Corbett"
    },
    {
      "name": "M. K. Alemu"
    },
    {
      "name": "B. D. Darge"
    },
    {
      "name": "L. K. HIlderbrand"
    },
    {
      "name": "K. A. Richardson"
    },
    {
      "name": "S. S. Ogonuwe"
    },
    {
      "name": "I. M. Blum"
    },
    {
      "name": "K. Shen"
    },
    {
      "name": "M. K. McGuire"
    },
    {
      "name": "D. H. Pandhi"
    },
    {
      "name": "L. W. Gallagher"
    },
    {
      "name": "J. M. Hunter"
    },
    {
      "affs": [
        0
      ],
      "name": "F. Grant"
    },
    {
      "name": "W. Simmons"
    },
    {
      "name": "L. Davis"
    },
    {
      "name": "P. Shields"
    },
    {
      "name": "S. Cooper"
    },
    {
      "name": "M. Rouse"
    },
    {
      "name": "K. S. Wilson-Lawson"
    },
    {
      "name": "C. Hughes-Culp"
    },
    {
      "name": "M. Howard"
    },
    {
      "name": "M. Monroe"
    },
    {
      "name": "M. Coleman"
    },
    {
      "name": "D. Leath"
    },
    {
      "name": "J. Butsch"
    },
    {
      "name": "N. Davis"
    },
    {
      "name": "J. Henry"
    },
    {
      "name": "P. Gregory"
    },
    {
      "affs": [
        0
      ],
      "name": "J. G. Grant"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/307f31crmb2em.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.10.13.26365095",
  "fulltext_url": "https://www.medrxiv.org/content/10.64898/2026.10.13.26365095v1.full",
  "id": "307f31crmb2em",
  "issns": [],
  "landing_url": "https://www.medrxiv.org/content/10.64898/2026.10.13.26365095v1",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "medrxiv",
      "neurology"
    ],
    [
      "openalex",
      "2739|Ethics in Clinical Research"
    ]
  ],
  "openalex": "W7222073126",
  "pdf_url": "https://www.medrxiv.org/content/10.64898/2026.10.13.26365095v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-13",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/307f31crmb2em.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:20:58Z",
      "native_id": "10.64898/2026.10.13.26365095",
      "source": "medrxiv",
      "url": "https://www.medrxiv.org/content/10.64898/2026.10.13.26365095v1"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "medrxiv:neurology",
      "subfield": "neurology"
    }
  ],
  "title": "Research attitudes mediate the association between educational attainment and willingness to participate in Alzheimer's disease research beyond Alzheimer's disease knowledge",
  "title_text": "Research attitudes mediate the association between educational attainment and willingness to participate in Alzheimer's disease research beyond Alzheimer's disease knowledge",
  "type": "preprint",
  "updated_at": "2026-10-30T12:20:58Z",
  "url": "https://research.draconitic.com/paper/307f31crmb2em",
  "venue": "medRxiv",
  "versions": []
}