{
  "abstract": "Introduction\n\nHepatosplenic cat-scratch disease (HS-CSD) is a rare manifestation of Bartonella henselae infection in immunocompetent adults and may closely mimic haematological malignancy.Case description\n\nA 62-year-old woman with a history of breast cancer presented with an eight-week history of fever, night sweats and weight loss. A fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET/CT) revealed hypermetabolic hepatosplenic lesions, retroperitoneal lymphadenopathy and a focal acetabular bone lesion, strongly suggesting stage IV lymphoma or metastatic disease. Bone marrow biopsy showed no evidence of malignancy; liver biopsy revealed caseous necrotising granulomas. Mycobacterial polymerase chain reaction (PCR) and cultures were negative. Bartonella serology demonstrated a high IgG titre (>1:1.280), while tissue PCR was borderline positive. Treatment with azithromycin and rifampicin for four weeks resulted in clinical improvement and resolution of constitutional symptoms.Conclusion\n\nHS-CSD can closely mimic advanced malignancy. In patients with prolonged fever, visceral lesions and feline exposure, B. henselae infection should be considered early in the diagnostic workup.Learning points\n\nHS-CSD may closely mimic advanced malignancy.Feline exposure should prompt consideration of Bartonella henselae infection in patients with prolonged fever and visceral lesions, to avoid unnecessary investigations or inappropriate treatments.",
  "abstract_shown": true,
  "affiliations": [
    "Department of infectious diseases, CHU UCL Yvoir, Namur, Belgium.",
    "Department of haematology, CHU UCL Yvoir, Namur, Belgium.",
    "Department of cardiology, CHU UCL Yvoir, Namur.",
    "Department of nuclear medicine, CHU UCL Yvoir, Namur, Belgium."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Marine Eliard"
    },
    {
      "affs": [
        1
      ],
      "name": "Pierre-Yves Sansen"
    },
    {
      "affs": [
        2
      ],
      "name": "Martin Benoit"
    },
    {
      "affs": [
        3
      ],
      "name": "Bruno Krug"
    },
    {
      "affs": [
        1
      ],
      "name": "Helene Vellemans"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/339pewb2hm3v0.bib",
  "cited_by": 0,
  "doi": "10.12890/2026_007477",
  "fulltext_url": "https://europepmc.org/articles/PMC13750771",
  "id": "339pewb2hm3v0",
  "issns": [
    "2284-2594"
  ],
  "landing_url": "https://europepmc.org/article/MED/43011688",
  "language": "eng",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Article"
    ],
    [
      "openalex",
      "2725|Bartonella species infections research"
    ]
  ],
  "openalex": "W7222622985",
  "pdf_url": "https://europepmc.org/articles/PMC13750771?pdf=render",
  "pmcid": "PMC13750771",
  "pmid": "43011688",
  "published": "2026-10-16",
  "publisher": "European Federation of Internal Medicine",
  "ris": "https://research.draconitic.com/paper/339pewb2hm3v0.ris",
  "sources": [
    {
      "first_seen": "2026-11-12T15:25:13Z",
      "native_id": "MED:43011688",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/43011688"
    },
    {
      "first_seen": "2026-11-14T12:23:17Z",
      "native_id": "PMC13750771",
      "source": "pmc",
      "url": "https://doi.org/10.12890/2026_007477"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2725|Bartonella species infections research",
      "subfield": "infectious-disease"
    }
  ],
  "title": "Granulomatous Hepatitis Due to Bartonella Henselae Mimicking Stage IV Malignancy.",
  "title_text": "Granulomatous Hepatitis Due to Bartonella Henselae Mimicking Stage IV Malignancy.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-14T12:23:17Z",
  "url": "https://research.draconitic.com/paper/339pewb2hm3v0",
  "venue": "European journal of case reports in internal medicine",
  "versions": []
}