{
  "abstract": "Objective\n\nTo assess the effect of air pollution on heart rate variability and pulmonary function in schoolchildren.Methods\n\nThis was a cross-sectional study with a convenience sample of schoolchildren living in a highly polluted area in Cubatão, São Paulo. Resting heart rate variability data were collected through cardiac monitoring, based on SDNN (standard deviation of NN intervals), rMSSD (root mean square of successive differences between NN intervals), and HFnu (high-frequency component in normalized units, an indicator of autonomic parasympathetic activity). In order to assess pulmonary function, spirometry was performed based on FEV1 (forced expiratory volume in the first second) and FEF25%-75% (forced expiratory flow between 25% and 75% of forced vital capacity). Pollutant concentration levels were provided by the São Paulo State Environment Company. Multiple linear regression was used to investigate associations between pollutant levels and physiological parameters, using Stata software version 12.0.Results\n\nSeventy-seven schoolchildren were assessed. Increased sulfur dioxide was associated with a reduction in HFnu: -0.68 (95% confidence interval - 95%CI -1.27; -0.11) in the daily average, -0.67 (95%CI -1.26; -0.07) over two days, and -1.29 (95%CI -2.21; -0.38) over three days. Ozone was also associated with a -0.32 (95%CI -0.62; -0.02) reduction in HFnu. Regarding pulmonary function, increased nitrogen dioxide was associated with a 0.23% reduction in FEV1 and a 0.30% reduction in FEF25%-75%.Conclusion\n\nSchoolchildren exposed to air pollution showed reduced heart rate variability and pulmonary function.",
  "abstract_shown": true,
  "affiliations": [
    "Escola Superior de Ciências da Santa Casa de Misericórdia de Vitória, Mestrado em Políticas Públicas e Desenvolvimento Local, Vitória, ES, Brazil Escola Superior de Ciências Santa Casa de Misericórdia de Vitória VitóriaES Brazil.",
    "Centro Universitário Faculdade de Medicina do ABC, Laboratório de Epidemiologia e Análises de Dado, Santo André, SP, Brazil Centro Universitário Faculdade de Medicina do ABC Laboratório de Epidemiologia e Análises de Dado Santo AndréSP Brazil."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Fernando Rocha Oliveira",
      "orcid": "0000-0002-6776-2072"
    },
    {
      "affs": [
        1
      ],
      "name": "Laércio da Silva Paiva",
      "orcid": "0000-0003-3646-2621"
    },
    {
      "affs": [
        0
      ],
      "name": "Roberta Ribeiro Batista Barbosa",
      "orcid": "0000-0001-9283-9097"
    },
    {
      "affs": [
        0
      ],
      "name": "Fabiana Rosa Neves Smiderle",
      "orcid": "0000-0001-5624-6673"
    },
    {
      "affs": [
        0
      ],
      "name": "Italla Maria Pinheiro Bezerra",
      "orcid": "0000-0002-8604-587X"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/33qrab9m9azfv.bib",
  "cited_by": 2,
  "doi": "10.1590/s2237-96222026v35e20250368.en",
  "fulltext_url": "https://europepmc.org/articles/PMC13686411",
  "id": "33qrab9m9azfv",
  "issns": [
    "1679-4974",
    "2237-9622"
  ],
  "landing_url": "https://europepmc.org/article/MED/42922790",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2307|Air Quality and Health Impacts"
    ]
  ],
  "openalex": "W7169755240",
  "pdf_url": "https://europepmc.org/articles/PMC13686411?pdf=render",
  "pmcid": "PMC13686411",
  "pmid": "42922790",
  "published": "2026-06-17",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/33qrab9m9azfv.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:21:02Z",
      "native_id": "MED:42922790",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42922790"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2307|Air Quality and Health Impacts",
      "subfield": "pharmacology-toxicology"
    }
  ],
  "title": "Effect of air pollution on heart rate variability and pulmonary function in schoolchildren: a cross-sectional study, Cubatão, Brazil, 2017.",
  "title_text": "Effect of air pollution on heart rate variability and pulmonary function in schoolchildren: a cross-sectional study, Cubatão, Brazil, 2017.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:21:02Z",
  "url": "https://research.draconitic.com/paper/33qrab9m9azfv",
  "venue": "Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil",
  "versions": []
}