{
  "abstract": "This cross-sectional study evaluated the quality of immunoglobulin A nephropathy (IgAN) care in Western Chongqing. It assessed patient demographics and associations between the Oxford Pathology Classification and laboratory indicators to identify priorities for local care improvement. We enrolled 73 patients with renal biopsy-confirmed IgAN from a tertiary hospital in Western Chongqing (January 2020–June 2023). Demographic data, Oxford Mesangial hypercellularity, Endocapillary proliferation, Segmental sclerosis, Tubular atrophy/interstitial fibrosis, and Crescents (histological classification system for IgAN) scores, and laboratory indicators were collected. Descriptive statistics were used to assess data completeness. Group comparisons and Spearman correlation analyses were performed. The 60 correlations between 12 laboratory indicators and 5 Mesangial hypercellularity, Endocapillary proliferation, Segmental sclerosis, Tubular atrophy/interstitial fibrosis, and Crescents (histological classification system for IgAN) components were evaluated as 1 Benjamini–Hochberg (BH) false discovery rate (FDR) family. The preoperative examination completion rate was 1.37%, whereas standardized renal pathology staining and IgAN pathological classification rates were both 100%; documented renin–angiotensin system blocker use among eligible patients and follow-up completion were 38.89% and 42.47%, respectively. After BH/FDR correction, sex was associated with occult blood (q = 0.013), red blood cell count (q = 0.000672), and hemoglobin concentration (q = 0.000436). Age group was associated with erythrocyte sedimentation rate (q = 0.009) and creatinine (q = 0.028), and body-weight group was associated with uric acid (q = 0.000188). In the Spearman analysis, the C score was positively associated with 24-h urinary protein (n = 66, ρ = 0.439, unadjusted P = .000226, q = 0.00451), whereas the M score was not (ρ = 0.115, P = .359, q = 0.552). This cross-sectional audit identified gaps in documented IgAN care and associations between pathology and laboratory profiles. The findings suggest local priorities for care improvement; the effects of management changes on clinical outcomes require longitudinal evaluation.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Nephrology, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, China",
    "General Practice School of Chongqing Medical University, Chongqing, China",
    "Department of Stomatology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Li Dong",
      "orcid": "0009-0000-1210-7444"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Min Cai"
    },
    {
      "affs": [
        2
      ],
      "name": "Lian Tan"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/33s3hg1mfh12s.bib",
  "cited_by": 0,
  "doi": "10.1097/md.0000000000051262",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13727175/?tool=EBI",
  "id": "33s3hg1mfh12s",
  "issns": [
    "0304-5412",
    "1536-5964",
    "0025-7974"
  ],
  "landing_url": "https://europepmc.org/article/PMC/PMC13727175",
  "language": "eng",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "5200"
    ],
    [
      "heading",
      "Observational Study"
    ],
    [
      "heading",
      "Research Article"
    ]
  ],
  "openalex": null,
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13727175/pdf/?tool=EBI",
  "pmcid": "PMC13727175",
  "pmid": null,
  "published": "2026-10-30",
  "publisher": "Wolters Kluwer Health",
  "ris": "https://research.draconitic.com/paper/33s3hg1mfh12s.ris",
  "sources": [
    {
      "first_seen": "2026-11-03T15:20:51Z",
      "native_id": "PMC:PMC13727175",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13727175"
    },
    {
      "first_seen": "2026-11-05T12:23:18Z",
      "native_id": "PMC13727175",
      "source": "pmc",
      "url": "https://doi.org/10.1097/md.0000000000051262"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "journal-openalex:F27",
      "subfield": "general"
    }
  ],
  "title": "Current status and optimization strategies for immunoglobulin a nephropathy management in the Western Region of Chongqing, China : A cross-sectional study",
  "title_text": "Current status and optimization strategies for immunoglobulin a nephropathy management in the Western Region of Chongqing, China : A cross-sectional study",
  "type": "peer-reviewed",
  "updated_at": "2026-11-06T12:22:54Z",
  "url": "https://research.draconitic.com/paper/33s3hg1mfh12s",
  "venue": "Medicine",
  "versions": []
}