{
  "abstract": "Duchenne muscular dystrophy (DMD) is a rare X-linked recessive disorder caused by mutations in the DMD gene, resulting in the absence of functional dystrophin. The loss of dystrophin disrupts the dystrophin-associated protein complex (DAPC), leading to progressive degeneration of skeletal and cardiac muscles. Clinically, DMD is characterized by proximal muscle weakness, respiratory insufficiency, and dilated cardiomyopathy. Here, we report the generation of three induced pluripotent stem cell (iPSC) lines reprogrammed from peripheral blood mononuclear cells (PBMCs) of patients with DMD. These patient-derived iPSC lines constitute a relevant human cellular model for studying disease-associated phenotypes and evaluating potential therapeutic strategies.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 18,
  "authors": [
    {
      "name": "Hamel Mahiou"
    },
    {
      "name": "Benjamin Marande"
    },
    {
      "name": "Lina El Kassar"
    },
    {
      "name": "Matthieu Lejars"
    },
    {
      "name": "Hassan Hayat"
    },
    {
      "name": "Christelle Kabore"
    },
    {
      "name": "Laura Brulle-Soumare"
    },
    {
      "name": "Pierre Joanne"
    },
    {
      "name": "Onnik Agbulut"
    },
    {
      "name": "Nejette Lallouche"
    },
    {
      "name": "Karim Wahbi"
    },
    {
      "name": "Teresinha Evangelista"
    },
    {
      "name": "Myriam Mederic"
    },
    {
      "name": "Sandrine Baghdoyan"
    },
    {
      "name": "Céline Bruge"
    },
    {
      "name": "Xavier Nissan"
    },
    {
      "name": "Karine Giraud-Triboult"
    },
    {
      "name": "Quentin Miagoux"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/345n7z6mxgkce.bib",
  "cited_by": 0,
  "doi": "10.1016/j.scr.2026.104074",
  "fulltext_url": null,
  "id": "345n7z6mxgkce",
  "issns": [
    "1876-7753"
  ],
  "landing_url": "https://hal.science/hal-05784443v1",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.sdv"
    ],
    [
      "openalex",
      "1312|Pluripotent Stem Cells Research"
    ]
  ],
  "openalex": "W7202228413",
  "pdf_url": "https://hal.science/hal-05784443/document",
  "pmcid": null,
  "pmid": null,
  "published": "2026-08-11",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/345n7z6mxgkce.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:50Z",
      "native_id": "hal-05784443",
      "source": "hal",
      "url": "https://hal.science/hal-05784443v1"
    }
  ],
  "subjects": [
    {
      "field": "biochemistry",
      "origin": "openalex:1312|Pluripotent Stem Cells Research",
      "subfield": "molecular-biology"
    }
  ],
  "title": "Generation and characterization of three human induced pluripotent stem cell lines from patients with Duchenne muscular dystrophy",
  "title_text": "Generation and characterization of three human induced pluripotent stem cell lines from patients with Duchenne muscular dystrophy",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:50Z",
  "url": "https://research.draconitic.com/paper/345n7z6mxgkce",
  "venue": "Stem Cell Research",
  "versions": []
}