{
  "abstract": "CON. Marked interindividual variability was observed in vascular responses and flavanone bioavailability, although treatment effects were unrelated to baseline endothelial function or flavanone exposure. Exploratory transcriptomic analyses suggested modulation of pathways involved in vascular biology following OJ and HESP. Under nutritionally realistic conditions, orange juice and hesperidin induced measurable biological engagement without detectable short-term vascular benefits, highlighting the complexity of linking flavanone exposure to functional vascular outcomes in humans.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 13,
  "authors": [
    {
      "name": "Caroline Gilcher"
    },
    {
      "name": "Dragan Milenkovic"
    },
    {
      "name": "Marie Taillandier"
    },
    {
      "name": "Tatjana Ruskovska"
    },
    {
      "name": "Christof Björn Steingass"
    },
    {
      "name": "Nicolas Macian"
    },
    {
      "name": "Marie Anne Verny"
    },
    {
      "name": "Rémi Evrard"
    },
    {
      "name": "Bruno Pereira"
    },
    {
      "name": "Cécile Gladine"
    },
    {
      "name": "Ralf Schweiggert"
    },
    {
      "name": "Gisèle Pickering"
    },
    {
      "name": "Christine Morand"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/3475rkg69zg4m.bib",
  "cited_by": 0,
  "doi": "10.1039/d6fo02778d",
  "fulltext_url": null,
  "id": "3475rkg69zg4m",
  "issns": [
    "2042-6496"
  ],
  "landing_url": "https://hal.science/hal-05747247v1",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.sdv"
    ],
    [
      "openalex",
      "2704|Phytochemicals and Antioxidant Activities"
    ]
  ],
  "openalex": "W7202349851",
  "pdf_url": null,
  "pmcid": null,
  "pmid": "42605853",
  "published": "2026-09-11",
  "publisher": "Cambridge : Royal Society of Chemistry",
  "ris": "https://research.draconitic.com/paper/3475rkg69zg4m.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:34Z",
      "native_id": "hal-05747247",
      "source": "hal",
      "url": "https://hal.science/hal-05747247v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "hal:0.sdv",
      "subfield": "general"
    }
  ],
  "title": "Orange juice and hesperidin increase flavanone exposure without detectable short-term vascular benefits: a randomized crossover trial",
  "title_text": "Orange juice and hesperidin increase flavanone exposure without detectable short-term vascular benefits: a randomized crossover trial",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:34Z",
  "url": "https://research.draconitic.com/paper/3475rkg69zg4m",
  "venue": "Food and Function",
  "versions": []
}