{
  "abstract": "Background/Objectives: Tricuspid annular plane systolic excursion (TAPSE) is routinely available in critical-care echocardiography, but the prognostic relevance of serial change is uncertain. We examined serial TAPSE and subsequent mortality among critically ill adults with reduced baseline TAPSE. Methods: This retrospective MIMIC-IV-ECHO cohort included adults with at least two TAPSE measurements and baseline TAPSE < 1.7 cm. Serial TAPSE status was classified as improved (increase >0.2 cm) or non-improved (change ≤0.2 cm). Cox regression evaluated 60-day mortality from the follow-up echocardiogram. Results: Among 227 patients, 101 (44.5%) were improved and 126 (55.5%) non-improved over a median interval of 10 days. Non-improved status was associated with higher subsequent mortality (adjusted hazard ratio 1.72, 95% confidence interval 1.06–2.80; p = 0.028). After adjustment for follow-up TAPSE, neither binary status nor continuous change was significantly associated with mortality. Conclusions: In this exploratory study, non-improved serial TAPSE was associated with higher 60-day mortality. Added prognostic value beyond follow-up TAPSE was not demonstrated.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Intensive Care Unit, China-Japan Friendship Hospital, Beijing 100029, China"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Shanshan Zhai"
    },
    {
      "affs": [
        0
      ],
      "name": "Dezhi Ren",
      "orcid": "0009-0002-6033-5606"
    },
    {
      "affs": [
        0
      ],
      "name": "Yongyi Chen"
    },
    {
      "affs": [
        0
      ],
      "name": "Hui Wang"
    },
    {
      "affs": [
        0
      ],
      "name": "Jun Duan"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/39yv868fea4tt.bib",
  "cited_by": 0,
  "doi": "10.3390/jcm15197753",
  "fulltext_url": null,
  "id": "39yv868fea4tt",
  "issns": [
    "2077-0383"
  ],
  "landing_url": "https://www.mdpi.com/2077-0383/15/19/7753",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2705|Cardiovascular Function and Risk Factors"
    ]
  ],
  "openalex": "W7221155199",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-08",
  "publisher": "MDPI AG",
  "ris": "https://research.draconitic.com/paper/39yv868fea4tt.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:20:00Z",
      "native_id": "10.3390/jcm15197753",
      "source": "crossref",
      "url": "https://www.mdpi.com/2077-0383/15/19/7753"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2705|Cardiovascular Function and Risk Factors",
      "subfield": "cardiovascular"
    }
  ],
  "title": "Serial TAPSE and Subsequent 60-Day Mortality Among Critically Ill Adults with Reduced Baseline TAPSE: A MIMIC-IV-ECHO Cohort Study",
  "title_text": "Serial TAPSE and Subsequent 60-Day Mortality Among Critically Ill Adults with Reduced Baseline TAPSE: A MIMIC-IV-ECHO Cohort Study",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:20:00Z",
  "url": "https://research.draconitic.com/paper/39yv868fea4tt",
  "venue": "Journal of Clinical Medicine",
  "versions": []
}