{
  "abstract": "The DEL phenotype is recognized as one of the weakest forms of the D antigen and can be identified through adsorption-elution testing or molecular analysis. At present, routine serologic or genetic screening for DEL variants is not performed among serologically RhD-negative blood donors in India. We describe a rare and clinically significant case of secondary anti-D alloimmunization in an RhD-negative female who developed anti-D antibodies following transfusion of a red blood cell (RBC) unit that was serologically typed as RhD-negative and weak D-negative, but was subsequently confirmed to possess the DEL phenotype. The DEL phenotype represents an extremely weak expression of the D antigen, which often remains undetectable by conventional serologic testing and requires adsorption-elution methods or molecular techniques for definitive identification. To the best of our knowledge, this is the first documented instance from India of anti-D alloimmunization arising specifically from transfusion of DEL phenotype red blood cells.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Transfusion Medicine, BLK-Max Super Specialty Hospital, New Delhi, India."
  ],
  "article_type": "case report",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Priyasha Prajapat"
    },
    {
      "affs": [
        0
      ],
      "name": "Rasika Dhawan Setia"
    },
    {
      "affs": [
        0
      ],
      "name": "Mitu Dogra"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/3bmjgg89knew2.bib",
  "cited_by": 0,
  "doi": "10.4103/ajts.ajts_242_25",
  "fulltext_url": "https://europepmc.org/articles/PMC13716266",
  "id": "3bmjgg89knew2",
  "issns": [
    "0973-6247",
    "1998-3565"
  ],
  "landing_url": "https://europepmc.org/article/MED/42953824",
  "language": "eng",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Case Report"
    ],
    [
      "openalex",
      "2720|Blood groups and transfusion"
    ]
  ],
  "openalex": "W7221057980",
  "pdf_url": "https://europepmc.org/articles/PMC13716266?pdf=render",
  "pmcid": "PMC13716266",
  "pmid": "42953824",
  "published": "2026-07-01",
  "publisher": "Wolters Kluwer -- Medknow Publications",
  "ris": "https://research.draconitic.com/paper/3bmjgg89knew2.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T00:20:41Z",
      "native_id": "MED:42953824",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42953824"
    },
    {
      "first_seen": "2026-11-01T12:23:18Z",
      "native_id": "PMC13716266",
      "source": "pmc",
      "url": "https://doi.org/10.4103/ajts.ajts_242_25"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2720|Blood groups and transfusion",
      "subfield": "general"
    }
  ],
  "title": "Secondary (anamnestic) anti D alloimmunization following transfusion of a DEL phenotype rhesus D negative unit: A case report highlighting the need for DEL screening in India.",
  "title_text": "Secondary (anamnestic) anti D alloimmunization following transfusion of a DEL phenotype rhesus D negative unit: A case report highlighting the need for DEL screening in India.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-01T12:23:18Z",
  "url": "https://research.draconitic.com/paper/3bmjgg89knew2",
  "venue": "Asian journal of transfusion science",
  "versions": []
}