{
  "abstract": "A vegan Indian woman in her late 20s was diagnosed with pulmonary tuberculosis. Imaging revealed a solitary hepatic mass five months after the initiation of antituberculosis therapy. Contrast-enhanced ultrasonography cannot distinguish between inflammation and malignancy. A biopsy revealed epithelioid cell granulomas without caseous necrosis, while a smear, culture, and PCR were negative. The therapy was continued without modification, and the hepatic lesion regressed within 7 months, consistent with a hepatic paradoxical reaction. This case illustrates that a new solitary hepatic mass emerging during antituberculosis therapy may represent a paradoxical reaction, and recognition of this entity may help clinicians avoid unnecessary regimen changes and invasive interventions, such as surgical resection.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 11,
  "authors": [
    {
      "name": "Yohei Takada"
    },
    {
      "name": "Takashi Inao"
    },
    {
      "name": "Ayumi Akamatsu"
    },
    {
      "name": "Kazuya Monden"
    },
    {
      "name": "Kojiro Otsuka"
    },
    {
      "name": "Kozo Ikuta"
    },
    {
      "name": "Chiho Ohbayashi"
    },
    {
      "name": "Riyo Fujiyama"
    },
    {
      "name": "Nobuya Kusunoki"
    },
    {
      "name": "Daiki Masuya"
    },
    {
      "name": "Yujiro Suzuki"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/3cq3997hzjdbc.bib",
  "cited_by": 0,
  "doi": "10.2169/internalmedicine.6629-25",
  "fulltext_url": "https://www.jstage.jst.go.jp/article/internalmedicine/65/21/65_6629-25/_article",
  "id": "3cq3997hzjdbc",
  "issns": [
    "1349-7235",
    "0918-2918"
  ],
  "landing_url": "https://www.jstage.jst.go.jp/article/internalmedicine/65/21/65_6629-25/_article",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "jstage-journal",
      "medicine/general"
    ],
    [
      "openalex",
      "2725|Tuberculosis Research and Epidemiology"
    ]
  ],
  "openalex": "W7140120273",
  "pdf_url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_6629-25/_pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-11-01",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/3cq3997hzjdbc.ris",
  "sources": [
    {
      "first_seen": "2026-11-01T12:20:57Z",
      "native_id": "10.2169/internalmedicine.6629-25",
      "source": "jstage",
      "url": "https://www.jstage.jst.go.jp/article/internalmedicine/65/21/65_6629-25/_article"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2725|Tuberculosis Research and Epidemiology",
      "subfield": "infectious-disease"
    }
  ],
  "title": "Liver Paradoxical Reaction Presenting as a Solitary Hepatic Mass during Antituberculosis Therapy",
  "title_text": "Liver Paradoxical Reaction Presenting as a Solitary Hepatic Mass during Antituberculosis Therapy",
  "type": "peer-reviewed",
  "updated_at": "2026-11-03T12:20:33Z",
  "url": "https://research.draconitic.com/paper/3cq3997hzjdbc",
  "venue": "Internal Medicine",
  "versions": []
}