{
  "abstract": "Operationally stable n-type organic mixed ionic-electronic conductors (OMIECs) remain a critical bottleneck for organic electrochemical transistors (OECTs) for application in bioelectronic and neuromorphic devices. However, several state-of-the-art n-type OMIECs suffer from performance decay and poor stability when operated in aqueous media. Inspired by myelin sheaths, we challenge the conventional \"π-backbone + hydrophilic side-chain\" design and propose a molecular architecture with fluorocarbon hydrophobic bridges to spatially segregate, at the molecular level, ionic and electronic pathways. By tuning the fluorocarbon bridge chain length in fluorocarbon-ethylene glycol chain substituents [-CH2(CF2)nCH2(OCH2CH2)5OMe = 2nFG; n = 1, 2, 3, 4, 6] of a DPP-CNTVT polymer series (2nFG-P), we balance electron transport, ion exchange, redox chemistry efficiency, and water incorporation. Extensive in situ spectroelectrochemistry, EIS, Raman, EQCM-D, AFM, and GIWAXS characterization reveals that tuning the length of the hydrophobic bridge enables good electron transport, suppresses excessive water incorporation, and enhances stability. Thus, the polymer with a mid-length bridge, 8FG-P (n = 4), achieves the greatest electron transport (μC* ∼ 157 F cm-1 V-1 s-1, μ ∼ 1.22 cm2 V-1 s-1), fastest response (τon/τoff = 2.6/1.5 ms), and retains >90% of the initial performance after 10,000 s of operation in water, a result independent of the polymer molecular weight. This strategy potentially expands OMIECs design principles and offers useful insights toward stable n-type OECT semiconductors.",
  "abstract_shown": true,
  "affiliations": [
    "Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming650091, China.",
    "School of Materials Science and Engineering, Georgia Institute of Technology, Atlanta, Georgia30332, United States.",
    "Southwest United Graduate School, Kunming650092, China.",
    "Department of Materials, The Hong Kong University of Science and Technology, Hong Kong999077, China."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Wang Feng"
    },
    {
      "affs": [
        0
      ],
      "name": "Shaodan Cai"
    },
    {
      "affs": [
        0
      ],
      "name": "Chao Deng"
    },
    {
      "affs": [
        0
      ],
      "name": "Bei Zhang"
    },
    {
      "affs": [
        1
      ],
      "name": "Mengge Wu"
    },
    {
      "affs": [
        0,
        2
      ],
      "name": "Jianhua Chen",
      "orcid": "0000-0002-4767-6310"
    },
    {
      "affs": [
        3,
        1
      ],
      "name": "Antonio Facchetti",
      "orcid": "0000-0002-8175-7958"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/3hw5mf102akzb.bib",
  "cited_by": 0,
  "doi": "10.1021/jacs.6c12196",
  "fulltext_url": "https://europepmc.org/articles/PMC13693380",
  "id": "3hw5mf102akzb",
  "issns": [
    "0002-7863",
    "1520-5126"
  ],
  "landing_url": "https://europepmc.org/article/MED/42912344",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2507|Conducting polymers and applications"
    ]
  ],
  "openalex": "W7221109294",
  "pdf_url": "https://europepmc.org/articles/PMC13693380?pdf=render",
  "pmcid": "PMC13693380",
  "pmid": "42912344",
  "published": "2026-10-01",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/3hw5mf102akzb.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:20:14Z",
      "native_id": "MED:42912344",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42912344"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:2507|Conducting polymers and applications",
      "subfield": "materials-polymers"
    }
  ],
  "title": "Myelin Sheath-Inspired Fluorocarbon Hydrophobic Bridges for Stable n-Type Organic Mixed Ionic-Electronic Conductors.",
  "title_text": "Myelin Sheath-Inspired Fluorocarbon Hydrophobic Bridges for Stable n-Type Organic Mixed Ionic-Electronic Conductors.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:20:14Z",
  "url": "https://research.draconitic.com/paper/3hw5mf102akzb",
  "venue": "Journal of the American Chemical Society",
  "versions": []
}