{
  "abstract": "AA amyloidosis is rare in resource-rich settings, but remains prevalent in regions with untreated infection, particularly tuberculosis. We describe a case in Australia of a 68-year-old Somali-born woman with recurrent small-bowel obstruction, weight loss, and retroperitoneal lymphadenopathy. While colonoscopy was macroscopically normal, small-bowel biopsies revealed Congo red-positive AA amyloidosis. Lymph-node biopsy showed histiocytes with granulomatous inflammation, and tuberculosis testing was negative. Given epidemiologic factors and chronic inflammation, culture-negative tuberculosis with AA amyloidosis sequelae was presumed. Empirical tuberculous treatment led to clinical improvement and resolution of PET-avid lymphadenopathy, highlighting an unusual case of infiltrative small-bowel disease.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Gastroenterology, Northern Health, Melbourne, Victoria, Australia",
    "Department of Infectious Disease, Northern Health, Melbourne, Victoria, Australia",
    "Department of Anatomical Pathology, Northern Health, Melbourne, Victoria, Australia"
  ],
  "article_type": "case report",
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Jacoba van Wees",
      "orcid": "0009-0008-2786-4278"
    },
    {
      "affs": [
        0
      ],
      "name": "Terry Yan"
    },
    {
      "affs": [
        1
      ],
      "name": "Robin Sia"
    },
    {
      "affs": [
        2
      ],
      "name": "Diana Moir"
    },
    {
      "affs": [
        0
      ],
      "name": "Irene Lu"
    },
    {
      "affs": [
        0
      ],
      "name": "Diana Lewis"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/3kmpg2axrcjjg.bib",
  "cited_by": 0,
  "doi": "10.14309/crj.0000000000002392",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13722498/?tool=EBI",
  "id": "3kmpg2axrcjjg",
  "issns": [
    "2326-3253"
  ],
  "landing_url": "https://europepmc.org/article/PMC/PMC13722498",
  "language": "eng",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Case Report"
    ],
    [
      "heading",
      "Small Bowel"
    ],
    [
      "openalex",
      "1312|Amyloidosis: Diagnosis, Treatment, Outcomes"
    ]
  ],
  "openalex": "W7224928758",
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13722498/pdf/?tool=EBI",
  "pmcid": "PMC13722498",
  "pmid": "42965233",
  "published": "2026-10-30",
  "publisher": "American College of Gastroenterology",
  "ris": "https://research.draconitic.com/paper/3kmpg2axrcjjg.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T12:21:37Z",
      "native_id": "PMC:PMC13722498",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13722498"
    },
    {
      "first_seen": "2026-11-03T12:22:59Z",
      "native_id": "PMC13722498",
      "source": "pmc",
      "url": "https://doi.org/10.14309/crj.0000000000002392"
    }
  ],
  "subjects": [
    {
      "field": "biochemistry",
      "origin": "openalex:1312|Amyloidosis: Diagnosis, Treatment, Outcomes",
      "subfield": "molecular-biology"
    }
  ],
  "title": "Small-Bowel Obstruction due to AA Amyloidosis in Presumed Extrapulmonary Tuberculosis",
  "title_text": "Small-Bowel Obstruction due to AA Amyloidosis in Presumed Extrapulmonary Tuberculosis",
  "type": "peer-reviewed",
  "updated_at": "2026-11-03T12:22:59Z",
  "url": "https://research.draconitic.com/paper/3kmpg2axrcjjg",
  "venue": "ACG case reports journal",
  "versions": []
}