{
  "abstract": "Background: We recently established that bendopnoea (breathlessness upon bending forward) is common with pleural effusion; however, it has never been reported or investigated in patients with pneumothorax. This exploratory study investigated the prevalence and clinical relevance of bendopnoea in pneumothorax. Methods: Patients with pneumothorax of any aetiology or size were eligible. The presence of bendopnoea and time-to-bendopnoea was measured by bending the patient forward for 60 s and was assessed at baseline and post lung re-expansion. Results: Fifty patients (median age 48 years; 78% male) with primary spontaneous (48%), secondary spontaneous (24%) or iatrogenic (28%) pneumothorax were included. Pneumothorax size ranged from 7 to 99% of the hemithorax on chest radiographs. Most patients (74%) received conservative management. On a questionnaire, 48% (24/50) patients reported they experienced bendopnoea which \"impacted daily life\". When bent forward, 32% (16/50) developed bendopnoea within 60 s. Patients with bendopnoea reported more breathlessness than those without bendopnoea on a 100 mm Visual Analogue Scale (VAS): median 46 [Q1-Q3 = 25-54] vs. 12 [3-32] mm, respectively, p = 0.0089; median difference -23 mm (95% CI -35 to -6). Those with bendopnoea showed a signal with worse chest pain on a 100 mm VAS for pain: median 28 [13-48] vs. 10 [2-42] mm, p = 0.0528; median difference -15 mm (95% CI -27 to 0). Shorter time-to-bendopnoea (i.e., worse bendopnoea) correlated with worse breathlessness (rs = -0.38, 95% CI -0.6 to -0.1; p = 0.0072) and more severe chest pain (rs = -0.29, 95% CI -0.5 to -0.007; p = 0.039). Conclusions: Bendopnoea can occur with pneumothorax, correlates with breathlessness and demonstrates a signal with worse chest pain.",
  "abstract_shown": true,
  "affiliations": [
    "Exercise Medicine Research Institute, Edith Cowan University, Joondalup, Perth, WA 6027, Australia.",
    "Pleural Medicine Unit, Institute for Respiratory Health, Nedlands, Perth, WA 6009, Australia.",
    "Centre for Innovative Pleural Research, Sir Charles Gairdner Hospital, Nedlands, Perth, WA 6009, Australia.",
    "Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Perth, WA 6009, Australia.",
    "School of Medicine, University of Western Australia, Crawley, Perth, WA 6009, Australia."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Bianca M Iacopetta",
      "orcid": "0009-0003-7510-5261"
    },
    {
      "affs": [
        2,
        3
      ],
      "name": "Niranjan Ananda Setty",
      "orcid": "0000-0002-5340-0329"
    },
    {
      "affs": [
        2,
        3
      ],
      "name": "Chloe Charlesworth"
    },
    {
      "affs": [
        3
      ],
      "name": "Michaela Donaghy",
      "orcid": "0009-0008-9745-0214"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Carolyn J Peddle-McIntyre"
    },
    {
      "affs": [
        1,
        2
      ],
      "name": "Ai Ling Tan",
      "orcid": "0009-0004-8956-0537"
    },
    {
      "affs": [
        1,
        2,
        3,
        4
      ],
      "name": "Y C Gary Lee",
      "orcid": "0000-0002-0036-511X"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/3m0by0x6nevzj.bib",
  "cited_by": 0,
  "doi": "10.3390/arm94050068",
  "fulltext_url": "https://europepmc.org/articles/PMC13701407",
  "id": "3m0by0x6nevzj",
  "issns": [
    "2451-4934",
    "2543-6031"
  ],
  "landing_url": "https://europepmc.org/article/MED/42930046",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2740|Pleural and Pulmonary Diseases"
    ]
  ],
  "openalex": "W7213980794",
  "pdf_url": "https://europepmc.org/articles/PMC13701407?pdf=render",
  "pmcid": "PMC13701407",
  "pmid": "42930046",
  "published": "2026-09-22",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/3m0by0x6nevzj.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:22:02Z",
      "native_id": "MED:42930046",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42930046"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2740|Pleural and Pulmonary Diseases",
      "subfield": "general"
    }
  ],
  "title": "The PASE Study: The Prevalence and Associations of Bendopnoea in Patients with Pneumothorax.",
  "title_text": "The PASE Study: The Prevalence and Associations of Bendopnoea in Patients with Pneumothorax.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:22:02Z",
  "url": "https://research.draconitic.com/paper/3m0by0x6nevzj",
  "venue": "Advances in respiratory medicine",
  "versions": []
}