{
  "abstract": "BackgroundVitamin K prophylaxis is universally recommended for newborns to prevent life threatening vitamin K deficiency bleeding. Although not on the immunization schedule, vitamin K prophylaxis is often coadministered with hepatitis B birth dose and erythromycin ophthalmic ointment, and rising hesitancy around vaccines/preventive care may spill over into vitamin K administration.\n\nMethodsWe conducted a retrospective cohort study using Truveta electronic health record data with linked mother-child dyads. Live births among mothers aged 15-49 from January 1, 2019 through June 30, 2026 were included. Vitamin K administration was defined as documentation on the birth date or following day. Logistic regression assessed sociodemographic predictors of non-receipt, and interrupted time series analysis evaluated changes after January 2026.\n\nResultsAmong 1,026,375 infants, 995,628 (96.97%) had documented vitamin K administration. Non-receipt increased from an average of 2.1% during 2019 -2022 to 4.3% in 2025 and 6.1% in 2026, reaching 8.10% in June 2026. Older maternal age, non-Hispanic or Latino ethnicity, Medicaid or unknown insurance, and year of delivery were associated with greater odds of non-receipt. After January 2026, there was no immediate step change, but the odds of vitamin K receipt declined an additional 10% per month (OR: 0.90; 95% CI, 0.88 -0.91).\n\nConclusionsVitamin K non-receipt increased over the study period and accelerated after January 2026. Because vitamin K recommendations were not changed by the January vaccine schedule, this association may reflect broader impacts to confidence in newborn preventive care. Future studies should examine causal mechanisms, parental decision-making, and associated clinical outcomes.",
  "abstract_shown": true,
  "affiliations": [
    "Truveta"
  ],
  "article_type": "PUBLISHAHEADOFPRINT",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "N. B. Masters"
    },
    {
      "name": "K. G. Farrar"
    },
    {
      "name": "E. Holler"
    },
    {
      "name": "J. M. Lancaster"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/3mcs8d36f1mbf.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.08.31.26361837",
  "fulltext_url": "https://www.medrxiv.org/content/10.64898/2026.08.31.26361837v1.full",
  "id": "3mcs8d36f1mbf",
  "issns": [],
  "landing_url": "https://www.medrxiv.org/content/10.64898/2026.08.31.26361837v1",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "medrxiv",
      "pediatrics"
    ],
    [
      "openalex",
      "2916|Vitamin K Research Studies"
    ]
  ],
  "openalex": "W7206202209",
  "pdf_url": "https://www.medrxiv.org/content/10.64898/2026.08.31.26361837v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-08-31",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/3mcs8d36f1mbf.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:31Z",
      "native_id": "10.64898/2026.08.31.26361837",
      "source": "medrxiv",
      "url": "https://www.medrxiv.org/content/10.64898/2026.08.31.26361837v1"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "medrxiv:pediatrics",
      "subfield": "reproductive-child"
    }
  ],
  "title": "Rising rate of non-receipt of vitamin K prophylaxis for newborns, January 2019 - June 2026",
  "title_text": "Rising rate of non-receipt of vitamin K prophylaxis for newborns, January 2019 - June 2026",
  "type": "preprint",
  "updated_at": "2026-10-30T12:17:31Z",
  "url": "https://research.draconitic.com/paper/3mcs8d36f1mbf",
  "venue": "medRxiv",
  "versions": []
}