{
  "abstract": "Crohn's disease is a chronic, transmural, and progressive inflammatory bowel disease characterized by cumulative structural damage and a high rate of recurrence. Although biologic agents have achieved considerable success in controlling inflammation, a substantial proportion of patients still require surgical intervention. In recent years, the treat-to-target concept—emphasizing objective control of inflammation and prevention of structural damage—has been progressively incorporated into the comprehensive management framework for Crohn's disease. Accordingly, surgery should no longer be viewed simply as a last resort after medical treatment failure. From the perspective of treat-to-target, this review evaluates the current status and challenges of surgical management in Crohn's disease, explores optimization and individualization of treatment decisions, and analyzes other important clinical management approaches and strategies.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, Guangdong, China"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Qiu Zhuoziqi"
    },
    {
      "affs": [
        0
      ],
      "name": "Chen Zhihui"
    },
    {
      "affs": [
        0
      ],
      "name": "Chen Chuangqi"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/3mrx48xqxvf5f.bib",
  "cited_by": 0,
  "doi": "10.19668/j.cnki.issn1674-0491.2026.04.003",
  "fulltext_url": "https://jcas.gxmuyfy.cn/en/wqll/paper.html?id=922140056083369984&cateName=Vol.4%20%20No.32%202026",
  "id": "3mrx48xqxvf5f",
  "issns": [
    "1674-0491"
  ],
  "landing_url": "https://doi.org/10.19668/j.cnki.issn1674-0491.2026.04.003",
  "language": "zh",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "RD1-811"
    ],
    [
      "openalex",
      "1311|Inflammatory Bowel Disease"
    ]
  ],
  "openalex": "W7223676924",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-08-01",
  "publisher": "Editorial Office of Journal of Colorectal & Anal Surgery",
  "ris": "https://research.draconitic.com/paper/3mrx48xqxvf5f.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:44:29Z",
      "native_id": "294ef73e79c34f889b399f21e0d32195",
      "source": "doaj",
      "url": "https://doi.org/10.19668/j.cnki.issn1674-0491.2026.04.003"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:1311|Inflammatory Bowel Disease",
      "subfield": "genetics-genomics"
    }
  ],
  "title": "Surgical management of Crohn's disease: current status and challenges",
  "title_text": "Surgical management of Crohn's disease: current status and challenges",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:44:29Z",
  "url": "https://research.draconitic.com/paper/3mrx48xqxvf5f",
  "venue": "结直肠肛门外科",
  "versions": []
}