{
  "abstract": "Objective: To determine whether Dermabond (2-octyl cyanoacrylate) provides superior lead stability to suture for percutaneous spinal cord stimulator (SCS) trial leads, and whether migration reflects patient-level factors rather than anchoring method.\n\nDesign: Prospective, randomized, within-patient controlled trial (ClinicalTrials.gov NCT05914311).\n\nSetting: Interventional Pain and Spine Medicine Center at an academic medical center.\n\nSubjects: Forty-eight adults (96 leads) undergoing bilateral thoracic percutaneous SCS trial implantation.\n\nMethods: Within each patient, one lead was randomized to Dermabond and the contralateral lead to suture. The primary outcome was absolute radiographic lead migration (mm) between placement and end-of-trial, both imaged upright. All analyses accounted for within-patient correlation; a post hoc non-inferiority framing used the a priori 9 mm clinically meaningful threshold.\n\nResults: Mean absolute migration was 9.15 ± 14.49 mm (Dermabond) and 10.60 ± 17.42 mm (suture); the paired difference was −1.46 mm (95% CI, −6.73 to 3.81; P = .58), with the upper bound well below the 9 mm threshold. In adjusted analyses, male sex (+8.17 mm; P = .036) and prior spine surgery (+7.08 mm; P = .048) predicted greater migration; body mass index (BMI), age, and fixation method did not. Clinically significant (≥9 mm) migration occurred in 27.1% of Dermabond and 22.9% of suture leads (McNemar P = .77).\n\nConclusions: Dermabond was not superior to suture but showed clinically comparable stability, supporting it as a noninvasive alternative. The stronger signal was at the patient level: male sex and prior spine surgery, but not BMI, predicted migration. Future efforts to reduce migration should target patient-level drivers rather than anchor choice.\n\nClinical trial registration number: ClinicalTrials.gov NCT05914311 (registered a priori).",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "name": "Robert W Hurley",
      "orcid": "0000-0001-6591-9390"
    },
    {
      "name": "Janus S Patel"
    },
    {
      "name": "Daniel J Bintrim"
    },
    {
      "name": "Jennifer B Oliver"
    },
    {
      "name": "Amelia Miranda"
    },
    {
      "name": "Tiye Rahmah"
    },
    {
      "name": "Carlyle P Hamsher"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/3qadpz5dv6rey.bib",
  "cited_by": 0,
  "doi": "10.1093/pm/pnag083",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13725065/",
  "id": "3qadpz5dv6rey",
  "issns": [
    "1526-2375",
    "1526-4637"
  ],
  "landing_url": "https://doi.org/10.1093/pm/pnag083",
  "language": "en",
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "AcademicSubjects/MED00010"
    ],
    [
      "heading",
      "Neuromodulation & Minimally Invasive Surgery Section"
    ],
    [
      "heading",
      "Original Research Article"
    ],
    [
      "openalex",
      "2703|Pain Management and Treatment"
    ]
  ],
  "openalex": "W7167222620",
  "pdf_url": "https://academic.oup.com/painmedicine/advance-article-pdf/doi/10.1093/pm/pnag083/68694069/pnag083.pdf",
  "pmcid": "PMC13725065",
  "pmid": "42398024",
  "published": "2026-07-03",
  "publisher": "Oxford University Press",
  "ris": "https://research.draconitic.com/paper/3qadpz5dv6rey.ris",
  "sources": [
    {
      "first_seen": "2026-11-04T12:23:31Z",
      "native_id": "PMC13725065",
      "source": "pmc",
      "url": "https://doi.org/10.1093/pm/pnag083"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2703|Pain Management and Treatment",
      "subfield": "surgery"
    }
  ],
  "title": "Dermabond versus suture fixation for spinal cord stimulator trial lead anchoring: a randomized within-patient controlled trial",
  "title_text": "Dermabond versus suture fixation for spinal cord stimulator trial lead anchoring: a randomized within-patient controlled trial",
  "type": "peer-reviewed",
  "updated_at": "2026-11-06T12:21:25Z",
  "url": "https://research.draconitic.com/paper/3qadpz5dv6rey",
  "venue": "Pain Medicine: The Official Journal of the American Academy of Pain Medicine",
  "versions": []
}