{
  "abstract": "In this study, the development of an ultrasound method for extraction of phenolic compounds from barley waste using acidic deep eutectic solvents (UAE-DES) was investigated. Optimization of the extraction parameters, which include extraction time, temperature, and ultrasound power (UP), was performed using the One-Factor-at-a-Time (OFAT) experimental design, followed by HPLC-PDA for determination of total quantified phenolic content (TQPC). In addition, the influence of water addition on TQPC was evaluated. The Maximum TQPC obtained was 5.78 mg/g using ChCl: formic acid at a molar ratio (1:2) and optimal conditions of (70 °C, 30 min, 80% UP, 10% water), and 4.67 mg/g, using ChCl: tartaric acid at a molar ratio (1:2) and optimal conditions of (70 °C, 25 min, 100% UP, and 20% water). The obtained TQPC was 5- and 4-fold higher in comparison with 70% methanol and 70% ethanol extraction. LC–MS-qTOF analysis of DES extracts revealed diverse phenolic compounds, while the concentration range of compounds obtained was as follows: ferulic acid (0.86–2.47 mg/g), catechin (0.12–2.16 mg/g), p-coumaric acid (0.12–0.32 mg/g), naringenin (0.54–0.86 mg/g), and apigenin (0.15–0.91 mg/g). SEM analysis confirmed enhanced accessibility of lignocellulose in DES-treated samples. The sustainability of UAE-DES extraction was assessed using AGREE, AGREEprep, CACI, BAGI, and CaFRI green tools. The grade assessment of each tool resulted in scores: 0.63 for AGREE, 0.57 for AGREEprep, 65 for CACI, 82.5 for BAGI, and 72 for CaFRI, indicating a greener extraction performance of UAE-DES in comparison with 70% methanol and 70% ethanol extraction.",
  "abstract_shown": true,
  "affiliations": [
    "Faculty of Forestry and Wood Sciences, Czech University of Life Sciences, Prague, Czechia",
    "Department of Food Analysis and Nutrition, University of Chemistry and Technology Prague, Prague, Czechia"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Bojana Bradić"
    },
    {
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        0
      ],
      "name": "Jakub Dušek"
    },
    {
      "affs": [
        1
      ],
      "name": "Jan Poustka"
    },
    {
      "affs": [
        1
      ],
      "name": "Chi Mai Nguyenova"
    },
    {
      "affs": [
        0
      ],
      "name": "Alina Kalyniukova"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/3qaxb5fgz6kx4.bib",
  "cited_by": 0,
  "doi": "10.3389/frans.2026.1895087",
  "fulltext_url": "https://www.frontiersin.org/articles/10.3389/frans.2026.1895087/full",
  "id": "3qaxb5fgz6kx4",
  "issns": [
    "2673-9283"
  ],
  "landing_url": "https://doi.org/10.3389/frans.2026.1895087",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "QD71-142"
    ],
    [
      "openalex",
      "1503|Ionic liquids properties and applications"
    ]
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  "openalex": "W7214749800",
  "pdf_url": "https://www.frontiersin.org/journals/analytical-science/articles/10.3389/frans.2026.1895087/pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-23",
  "publisher": "Frontiers Media S.A.",
  "ris": "https://research.draconitic.com/paper/3qaxb5fgz6kx4.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:43:12Z",
      "native_id": "864211eae9d2457ba0285d577250bd2c",
      "source": "doaj",
      "url": "https://doi.org/10.3389/frans.2026.1895087"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1503|Ionic liquids properties and applications",
      "subfield": "catalysis"
    }
  ],
  "title": "Selective extraction of phenolic compounds from barley waste using deep eutectic solvents",
  "title_text": "Selective extraction of phenolic compounds from barley waste using deep eutectic solvents",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:43:12Z",
  "url": "https://research.draconitic.com/paper/3qaxb5fgz6kx4",
  "venue": "Frontiers in Analytical Science",
  "versions": []
}