{
  "abstract": "Background Objective This study aimed to evaluate whether PVi and IJV-VI demonstrate sufficient agreement and trending ability to support their clinical interchangeability during laparoscopic living donor nephrectomy. Methods A prospective observational concordance study was conducted in adult patients undergoing elective laparoscopic living donor nephrectomy under mechanical ventilation. Simultaneous paired measurements of PVi and IJV-VI were obtained every 15 minutes during surgery. Agreement between methods was assessed using repeated-measures Bland–Altman analysis. Trending ability was evaluated using polar plot and four-quadrant plot analyses. Results Thirty-six patients were included, providing 366 paired intraoperative measurements. Bland–Altman analysis demonstrated a small overall bias of 0.06% (95%CI −0.21 to 0.39), with wide 95% limits of agreement ranging from −5.10% to 5.22% and a global percentage error of 55.96% (95% CI 37.81–74.17). Polar plot analysis showed poor trending ability, with an angular bias of 14.2°, angular dispersion of 117°, and only 34.5% of vectors within the clinically acceptable ±30° zone. Four-quadrant analysis demonstrated an overall concordance rate of 84.7% after applying a central exclusion zone. Conclusion Although PVi and IJV-VI demonstrated a strong positive association during laparoscopic living donor nephrectomy, agreement and trending ability between methods were limited. Main Points PVi and IJV-VI showed a strong positive association, but this did not translate into adequate agreement. Repeated-measures Bland–Altman analysis demonstrated minimal bias but wide limits of agreement and a high percentage error. Trending ability between both methods was poor, particularly in polar plot analysis. PVi and IJV-VI should not be considered clinically interchangeable during laparoscopic living donor nephrectomy.",
  "abstract_shown": true,
  "affiliations": [
    "Instituto Mexicano del Seguro Social"
  ],
  "article_type": "PUBLISHAHEADOFPRINT",
  "arxiv": null,
  "author_total": 11,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "D. Escarraman Martinez"
    },
    {
      "name": "S. Sanchez Brito"
    },
    {
      "name": "E. Perez Lozano"
    },
    {
      "name": "C. A. Escorza Molina"
    },
    {
      "name": "L. Noriega Salas"
    },
    {
      "name": "R. Candelaria Olguin"
    },
    {
      "name": "O. R. Perez Nieto"
    },
    {
      "name": "M. A. Guerrero Gutierrez"
    },
    {
      "name": "G. A. Solis Perez"
    },
    {
      "name": "I. Rodriguez Guevara"
    },
    {
      "name": "L. C. Galeana Gonzalez"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/3qww7mwh7t38x.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.09.11.26362695",
  "fulltext_url": "https://www.medrxiv.org/content/10.64898/2026.09.11.26362695v1.full",
  "id": "3qww7mwh7t38x",
  "issns": [],
  "landing_url": "https://www.medrxiv.org/content/10.64898/2026.09.11.26362695v1",
  "language": null,
  "licence": "PDM-1.0",
  "licence_label": "Public domain",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/publicdomain/mark/1.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "medrxiv",
      "anesthesia"
    ],
    [
      "openalex",
      "2746|Hemodynamic Monitoring and Therapy"
    ]
  ],
  "openalex": "W7213317689",
  "pdf_url": "https://www.medrxiv.org/content/10.64898/2026.09.11.26362695v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-11",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/3qww7mwh7t38x.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:33Z",
      "native_id": "10.64898/2026.09.11.26362695",
      "source": "medrxiv",
      "url": "https://www.medrxiv.org/content/10.64898/2026.09.11.26362695v1"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "medrxiv:anesthesia",
      "subfield": "surgery"
    }
  ],
  "title": "Interchangeability Between Pleth Variability Index and Internal Jugular Vein Variability Index During Laparoscopic Living Donor Nephrectomy: A Prospective Observational Concordance Study",
  "title_text": "Interchangeability Between Pleth Variability Index and Internal Jugular Vein Variability Index During Laparoscopic Living Donor Nephrectomy: A Prospective Observational Concordance Study",
  "type": "preprint",
  "updated_at": "2026-10-30T12:18:33Z",
  "url": "https://research.draconitic.com/paper/3qww7mwh7t38x",
  "venue": "medRxiv",
  "versions": []
}