{
  "abstract": "Corrective osteotomy for severe spinal deformity requires vertebral shortening, but the safe degree of shortening remains uncertain. This study used fluid-structure interaction finite element analysis to investigate how graded vertebral shortening affects cerebrospinal fluid (CSF) dynamics and anterior spinal artery (ASA) perfusion. A three-dimensional T1-T12 model was reconstructed from computed tomography data obtained from a 16-year-old male with scoliosis. Posterior vertebral column resection at T8/T9 was simulated in four conditions: no shortening and shortening by one-third, one-half, and two-thirds. Coupled CSF-dura and blood-vessel wall models were used to quantify pressure, wall shear stress, flow velocity, structural stress, and displacement. With shortening of up to one-half, CSF wall shear stress (~ 0.04 Pa) and velocity (~ 0.014 m/s) remained stable, whereas ASA luminal pressure and velocity declined gradually together with vessel-wall stress and displacement, indicating preserved hemodynamic compensation and mechanical unloading. At two-thirds shortening, CSF wall shear stress (0.4998 Pa) and velocity (0.16009 m/s) increased by approximately 12-fold and 11-fold, respectively; dural stress increased by approximately 34%, whereas displacement increased by only 1.2%, demonstrating nonlinear stress-displacement decoupling. ASA luminal pressure, velocity, vessel-wall stress, and displacement also rebounded to their highest values. In this patient-specific model, shortening up to one-half was associated with relative stability of CSF dynamics and progressive vascular unloading, whereas two-thirds shortening produced marked nonlinear changes in CSF and ASA-related biomechanical variables. These findings suggest a model-derived biomechanical transition between one-half and two-thirds shortening; however, this transition should not be interpreted as a clinically validated safety threshold.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "name": "Alimujiang Yusufu"
    },
    {
      "name": "Abudula Abulaiti"
    },
    {
      "name": "Abuduwupuer Haibier",
      "orcid": "0000-0001-7420-9761"
    },
    {
      "name": "Yuan Ma"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/3wag67na3c6a7.bib",
  "cited_by": 0,
  "doi": "10.1038/s41598-026-71867-7",
  "fulltext_url": "https://doi.org/10.1038/s41598-026-71867-7",
  "id": "3wag67na3c6a7",
  "issns": [
    "2045-2322"
  ],
  "landing_url": "https://www.nature.com/articles/s41598-026-71867-7",
  "language": "en",
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0",
  "metadata_licence": null,
  "native_subjects": [
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      "lcc",
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      "lcc",
      "R"
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      "openalex",
      "2746|Scoliosis diagnosis and treatment"
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  "pdf_url": "https://www.nature.com/articles/s41598-026-71867-7_reference.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-01",
  "publisher": "Springer Science and Business Media LLC",
  "ris": "https://research.draconitic.com/paper/3wag67na3c6a7.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:34Z",
      "native_id": "10.1038/s41598-026-71867-7",
      "source": "crossref",
      "url": "https://www.nature.com/articles/s41598-026-71867-7"
    },
    {
      "first_seen": "2026-11-08T14:20:57Z",
      "native_id": "02784631ad014a22891e1d88074ac538",
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      "url": "https://doi.org/10.1038/s41598-026-71867-7"
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  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2746|Scoliosis diagnosis and treatment",
      "subfield": "surgery"
    }
  ],
  "title": "Effects of vertebral shortening during corrective osteotomy for spinal deformity on spinal cord biomechanics and cerebrospinal fluid-anterior spinal artery fluid-structure interaction",
  "title_text": "Effects of vertebral shortening during corrective osteotomy for spinal deformity on spinal cord biomechanics and cerebrospinal fluid-anterior spinal artery fluid-structure interaction",
  "type": "peer-reviewed",
  "updated_at": "2026-11-08T14:20:57Z",
  "url": "https://research.draconitic.com/paper/3wag67na3c6a7",
  "venue": "Scientific Reports",
  "versions": []
}