{
  "abstract": "Background\n\nMany Canadians experience prolonged pain, uncertainty, and stigma before receiving an endometriosis diagnosis, with delays averaging 11 years from symptom onset. Endometriosis, defined by the presence of endometrial-like tissue outside the uterine cavity, impacts 10% of Canadian women and approximately 9% of transgender men. Existing screening measures are limited because they often focus on advanced disease and were developed outside Canada.Aims\n\nThe aim of this study is to revise the ENDOPAIN-4D screening measure to match a Canadian young adult (age 18-25) population.Methods\n\nUsing a participatory approach, the study involved four phases: an initial Delphi consensus survey with Canadian endometriosis experts; a virtual working meeting with a purposively selected subgroup; a second Delphi survey with working group members to refine proposed changes and reach consensus; and a third Delphi to collect final feedback. Participants included people with lived and living experience of endometriosis, gynecologists, pain medicine specialists focused on chronic pelvic pain, primary care providers, and other healthcare professionals involved in endometriosis care.Results\n\nSixty-five experts participated in the first Delphi round. Five major themes were identified: conceptual appropriateness of domains, question clarity, response option clarity, item redundancy, and simplification for a Canadian young adult audience. Fifteen experts participated in the working meeting and second Delphi round, where they refined item wording, clarified core concepts, and finalized items for the revised screening measure.Conclusions\n\nThis study adapted the ENDOPAIN-4D for Canadian young adults, resulting in a 22-item, five-domain screening measure called Screening for Early Endometriosis Detection (SEED).",
  "abstract_shown": true,
  "affiliations": [
    "Toronto Academic Pain Medicine Institute (TAPMI), Women's College Hospital, Toronto, Ontario, Canada.",
    "Department of Anesthesiology and Pain Medicine, University of Toronto, Toronto, Ontario, Canada.",
    "Centre of Excellence for Women's Health, Vancouver, British Columbia, Canada.",
    "Department of Obstetrics and Gynecology, McMaster University, Hamilton, Ontario, Canada.",
    "Department of Obstetrics and Gynecology, Department of Anesthesiology, Perioperative and Pain Medicine, Cumming School of Medicine, Calgary, Alberta, Canada.",
    "Department of Obstetrics and Gynecology, University of Toronto, Toronto, Ontario, Canada.",
    "Department of Obstetrics and Gynecology, Sinai Health System, Toronto, Ontario, Canada.",
    "Department of Family Medicine, University of Ottawa, Ottawa, Ontario, Canada.",
    "Bruyere Health Research Institute, Ottawa, Ontario, Canada.",
    "Department of Pediatrics, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, British Columbia, Canada.",
    "The Endometriosis Network Canada, Toronto, Ontario, Canada."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 12,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Rachael Bosma"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Brittany N Rosenbloom"
    },
    {
      "affs": [
        0
      ],
      "name": "Adriano Nella"
    },
    {
      "affs": [
        0,
        2
      ],
      "name": "Lindsay Wolfson"
    },
    {
      "affs": [
        3
      ],
      "name": "Mathew Leonardi"
    },
    {
      "affs": [
        4
      ],
      "name": "Magali Robert"
    },
    {
      "affs": [
        5,
        6
      ],
      "name": "M Jonathon Solnik"
    },
    {
      "affs": [
        7,
        8
      ],
      "name": "Arun Radhakrishnan"
    },
    {
      "affs": [
        9
      ],
      "name": "Katelynn E Boerner"
    },
    {
      "affs": [
        10
      ],
      "name": "Philippa Bridge-Cook"
    },
    {
      "affs": [
        10
      ],
      "name": "Katelyn Luciani"
    },
    {
      "affs": [
        0
      ],
      "name": "Tania Di Renna"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/3yb0acmwr3pn3.bib",
  "cited_by": 0,
  "doi": "10.1080/24740527.2026.2729539",
  "fulltext_url": "https://europepmc.org/articles/PMC13679329",
  "id": "3yb0acmwr3pn3",
  "issns": [
    "2474-0527"
  ],
  "landing_url": "https://europepmc.org/article/MED/42898862",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2743|Endometriosis Research and Treatment"
    ]
  ],
  "openalex": "W7221874031",
  "pdf_url": "https://europepmc.org/articles/PMC13679329?pdf=render",
  "pmcid": "PMC13679329",
  "pmid": "42898862",
  "published": "2026-10-15",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/3yb0acmwr3pn3.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:33Z",
      "native_id": "MED:42898862",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42898862"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2743|Endometriosis Research and Treatment",
      "subfield": "reproductive-child"
    }
  ],
  "title": "Screening for Early Endometriosis Detection (SEED): Co-development of a Symptom-Based Screening Measure for Canadian Young Adults in Primary Care.",
  "title_text": "Screening for Early Endometriosis Detection (SEED): Co-development of a Symptom-Based Screening Measure for Canadian Young Adults in Primary Care.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:33Z",
  "url": "https://research.draconitic.com/paper/3yb0acmwr3pn3",
  "venue": "Canadian journal of pain = Revue canadienne de la douleur",
  "versions": []
}