{
  "abstract": "Objective\n\nTo evaluate and characterize patients with presumed ocular toxoplasmosis using combined clinical and serological approaches in the municipality of Três Lagoas, Mato Grosso do Sul, Brazil.Methods\n\nThis cross-sectional quantitative study included 85 patients with presumed Toxoplasma gondii related retinochoroiditis referred from the public healthcare system. Participants underwent ophthalmologic examination and serological testing for anti-T. gondii IgG and IgM antibodies. Patients were classified into control (G1), active lesion (G2), and cicatricial lesion (G3) groups.Results\n\nOverall, 76.5% of patients were positive for anti-T. gondii IgG, while 3.5% were positive for IgM. Most patients with cicatricial lesions (G3) were IgG-positive (31/33). In contrast, IgM positivity was restricted to a small subset of patients (3/13) with active lesions (G2). Ophthalmologic evaluation demonstrated that unilateral disease predominated (78.2%), with lesions mainly located in the posterior pole (52.8%). Morphologically, round-to-ovoid lesions were most frequent (60.0%), followed by amoeboid (16.0%), placoid (8.0%), and wedge-shaped and punctate (4.0% each) patterns. Mean lesion size among evaluable eyes was 16.2 mm².Conclusion\n\nThe analyses provide data that contribute to the understanding of the clinical characteristics of the disease, ocular behavior, and serological findings. Consequently, preventive measures may be implemented, reducing risk factors and improving patients' quality of life.",
  "abstract_shown": true,
  "affiliations": [
    "Universidade Federal do Mato Grosso do Sul, Três Lagoas, MS, Brazil.",
    "Department of Dermatological, Infectious and Parasitic Diseases, Faculdade de Medicina de São José do Rio Preto, FAMERP Toxoplasma Research Group, Avenida Brigadeiro Faria Lima, 5416, São José do Rio Preto, SP, 15090-000, Brazil.",
    "Department of Dermatological, Infectious and Parasitic Diseases, Faculdade de Medicina de São José do Rio Preto, FAMERP Toxoplasma Research Group, Avenida Brigadeiro Faria Lima, 5416, São José do Rio Preto, SP, 15090-000, Brazil. cinara.brandao@famerp.br."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 12,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Alexsandra Passarelli Giabardo Marques"
    },
    {
      "affs": [
        1
      ],
      "name": "Luiza Roschel Zaunrith"
    },
    {
      "affs": [
        1
      ],
      "name": "Danilo Donizete da Silva"
    },
    {
      "affs": [
        1
      ],
      "name": "Aparecida Perpétuo Silveira Carvalho"
    },
    {
      "affs": [
        1
      ],
      "name": "Fernando Henrique Antunes Murata"
    },
    {
      "affs": [
        1
      ],
      "name": "Rubens Camargo Siqueira"
    },
    {
      "affs": [
        0
      ],
      "name": "Lucas Gazarini",
      "orcid": "0000-0003-4771-4871"
    },
    {
      "affs": [
        0
      ],
      "name": "Edis Belini Júnior"
    },
    {
      "affs": [
        0
      ],
      "name": "Julie Massayo Maeda Oda"
    },
    {
      "affs": [
        1
      ],
      "name": "Christiane Maria Ayo"
    },
    {
      "affs": [
        1
      ],
      "name": "Luiz Carlos de Mattos"
    },
    {
      "affs": [
        2
      ],
      "name": "Cinara Cássia Brandão",
      "orcid": "0000-0002-4836-3113"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/434zsqp6m7fhp.bib",
  "cited_by": 0,
  "doi": "10.1007/s10792-026-04302-5",
  "fulltext_url": "https://europepmc.org/articles/PMC13676675",
  "id": "434zsqp6m7fhp",
  "issns": [
    "0165-5701",
    "1573-2630"
  ],
  "landing_url": "https://europepmc.org/article/MED/42891856",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2405|Toxoplasma gondii Research Studies"
    ]
  ],
  "openalex": "W7222821857",
  "pdf_url": "https://europepmc.org/articles/PMC13676675?pdf=render",
  "pmcid": "PMC13676675",
  "pmid": "42891856",
  "published": "2026-10-17",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/434zsqp6m7fhp.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:46Z",
      "native_id": "MED:42891856",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42891856"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:2405|Toxoplasma gondii Research Studies",
      "subfield": "microbiology"
    }
  ],
  "title": "Clinical and imaging characterization of ocular toxoplasmosis in a Central-West Brazilian population.",
  "title_text": "Clinical and imaging characterization of ocular toxoplasmosis in a Central-West Brazilian population.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:18:46Z",
  "url": "https://research.draconitic.com/paper/434zsqp6m7fhp",
  "venue": "International ophthalmology",
  "versions": []
}